Functionalized biocatalytical compositions
AssigneePerseo Pharma AG
InventorsEmilie LAPRÉVOTTE, Miquel CATALA, Yves Victor René DUDAL, Patrick SHAHGALDIAN
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Abstract
The present invention relates to a composition comprising a solid carrier, an enzyme or a fragment thereof immobilized on the surface of the solid carrier, a protective layer to protect the enzyme or the fragment thereof by embedding the enzyme or the fragment thereof, and a functional constituent immobilized on the surface of the protective layer. The present invention also relates to a method for the prevention, delay of progression or treatment of lung cancer in a subject using said composition and methods of producing said composition.
Claims15
A composition comprising a solid carrier, an enzyme or a fragment thereof immobilized on the surface of the solid carrier, a protective layer to protect the enzyme or the fragment thereof by embedding the enzyme or the fragment thereof, and a functional constituent immobilized on the surface of the protective layer, wherein the particle size of the solid carrier is between 15 nm and 40 nm.
A method of producing a composition, the composition comprising a solid carrier wherein the particle size of the solid carrier is between 15 nm and 40 nm, an enzyme or a fragment thereof immobilized on the surface of the solid carrier, a protective layer to protect the enzyme or the fragment thereof by embedding the enzyme or the fragment thereof, and a functional constituent immobilized on the surface of the protective layer, the method comprising the following steps:
- (a) providing a solid carrier, wherein the particle size of the solid carrier is between 15 nm and 40 nm;
- (b) immobilizing an enzyme or a fragment thereof on the solid carrier;
- (c) forming a protective layer on the surface of the solid carrier to protect the enzyme or the fragment thereof immobilized on the solid carrier;
- (d) immobilizing a functional constituent on the surface of the protective layer.
Dependencies are inferred from the claim text.