C12N 9/1252
Dna-directed dna polymerase , i.e. dna replicase
Official title: {DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase}
C12N9/1252 (Dna-directed dna polymerase , i.e. dna replicase) appears on 967 US grants and 1,256 published applications in this corpus.
Search patents in C12N- Granted patents
- 967
- Published applications
- 1,256
- Assignees
- 410
- Inventors
- 1,938
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1988 | 1 | 0 |
| 1989 | 2 | 0 |
| 1990 | 5 | 0 |
| 1991 | 4 | 0 |
| 1992 | 6 | 0 |
| 1993 | 8 | 0 |
| 1994 | 7 | 0 |
| 1995 | 13 | 0 |
| 1996 | 14 | 0 |
| 1997 | 19 | 0 |
| 1998 | 25 | 0 |
| 1999 | 24 | 0 |
| 2000 | 19 | 0 |
| 2001 | 25 | 3 |
| 2002 | 23 | 27 |
| 2003 | 19 | 47 |
| 2004 | 12 | 39 |
| 2005 | 13 | 39 |
| 2006 | 16 | 30 |
| 2007 | 11 | 31 |
| 2008 | 17 | 23 |
| 2009 | 13 | 36 |
| 2010 | 19 | 39 |
| 2011 | 21 | 53 |
| 2012 | 13 | 29 |
| 2013 | 23 | 32 |
| 2014 | 42 | 55 |
| 2015 | 33 | 42 |
| 2016 | 54 | 65 |
| 2017 | 47 | 68 |
| 2018 | 54 | 53 |
| 2019 | 34 | 53 |
| 2020 | 56 | 77 |
| 2021 | 54 | 61 |
| 2022 | 42 | 62 |
| 2023 | 47 | 73 |
| 2024 | 51 | 94 |
| 2025 | 49 | 71 |
| 2026 | 32 | 54 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- DNA polymerase variant with improved discrimination of genetic variants29 Sep 2026US 12,747,469 B2Genotech Corp.
- Marine DNA polymerase I15 Sep 2026US 12,735,736 B2Universitetet I Tromso—Norges Arktiske Universitet
- Nucleic acid amplification4 Aug 2026US 12,698,485 B2Life Technologies Corporation
- PUMA1 polymerases and uses thereof28 Jul 2026US 12,692,484 B210x Genomics, Inc.
- Thermostable purified reverse transcriptase and methods of use28 Jul 2026US 12,692,525 B1
- Polymerase variants8 Oct 2026US 2026/0308540 A1Twist Bioscience Corporation
- Methods of engineering cells with mutated genomes using intact large cargo transfer systems8 Oct 2026US 2026/0308568 A1
- Therapeutic circular dna forms1 Oct 2026US 2026/0294957 A1Flagship Pioneering Innovations Vii, LLC
- Compositions, Methods, and Systems for Genomic Editing24 Sep 2026US 2026/0286329 A1Intellia Therapeutics, Inc.
- Novel method for isothermal amplification of padlock probes for nucleic acid detection and phi29 dna polymerase variants24 Sep 2026US 2026/0286424 A1Consejo Superior de Investigaciones Cientificas
Most cited
By later US patents
- Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme2,156US 4,965,188 ACetus Corporation · 1990
- Purified thermostable enzyme619US 4,889,818 ACetus Corporation · 1989
- Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity529US 7,211,414 B2Visigen Biotechnologies, Inc. · 2007
- Thermostable DNA polymerase with enhanced thermostability and enhanced length and efficiency of primer extension453US 5,436,149 A1995
- Detection of nucleic acids by multiple sequential invasive cleavages311US 5,994,069 AThird Wave Technologies, Inc. · 1999