C12N 5/067
Hepatocytes
Official title: {Hepatocytes}
C12N5/067 (Hepatocytes) appears on 605 US grants and 1,259 published applications in this corpus.
Search patents in C12N- Granted patents
- 605
- Published applications
- 1,259
- Assignees
- 582
- Inventors
- 2,212
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 2 | 0 |
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 2 | 0 |
| 1991 | 2 | 0 |
| 1992 | 2 | 0 |
| 1993 | 1 | 0 |
| 1994 | 2 | 0 |
| 1995 | 2 | 0 |
| 1996 | 7 | 0 |
| 1997 | 7 | 0 |
| 1998 | 8 | 0 |
| 1999 | 14 | 0 |
| 2000 | 11 | 0 |
| 2001 | 8 | 6 |
| 2002 | 6 | 21 |
| 2003 | 9 | 25 |
| 2004 | 5 | 31 |
| 2005 | 4 | 49 |
| 2006 | 10 | 26 |
| 2007 | 10 | 42 |
| 2008 | 15 | 40 |
| 2009 | 14 | 40 |
| 2010 | 10 | 40 |
| 2011 | 14 | 37 |
| 2012 | 13 | 35 |
| 2013 | 19 | 54 |
| 2014 | 30 | 39 |
| 2015 | 26 | 48 |
| 2016 | 27 | 65 |
| 2017 | 32 | 64 |
| 2018 | 32 | 70 |
| 2019 | 36 | 84 |
| 2020 | 33 | 65 |
| 2021 | 36 | 64 |
| 2022 | 33 | 80 |
| 2023 | 29 | 61 |
| 2024 | 29 | 61 |
| 2025 | 37 | 62 |
| 2026 | 24 | 50 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Generation of uniform hepatocytes from human embryonic stem cells by inhibiting TGF-beta and methods of maintaining hepatic cultures15 Sep 2026US 12,734,197 B2Wisconsin Alumni Research Foundation
- Method for expanding hepatocyte in vitro and application1 Sep 2026US 12,723,235 B2Center for Excellence In Molecular Cell Science, Chinese Academy of Sciences
- Method for producing cell aggregate1 Sep 2026US 12,723,236 B2Osaka University
- Method for differentiating pluripotent stem cells into desired cell type25 Aug 2026US 12,716,053 B2Keio University
- Huntingtin (HTT) iRNA agent compositions and methods of use thereof18 Aug 2026US 12,709,748 B2Alnylam Pharmaceuticals, Inc.
- Genetically engineered human fetal liver niche as platform for biomanufacturing of hematopoietic stem cells1 Oct 2026US 2026/0297528 A1Arizona Board of Regents on behalf of Arizona State University
- Use of nucleic acid molecule in preparation of drug for treating liver disease1 Oct 2026US 2026/0297576 A1Guangxiu-Gaoxin Life Sciences Co., Ltd. Hunan
- Compositions and methods for silencing ugt1a1 gene expression1 Oct 2026US 2026/0297589 A1Alnylam Pharmaceuticals, Inc.
- Culture media and conditions for in vitro expansion and/or maturation of hepatocytes24 Sep 2026US 2026/0286311 A1Satellite Biosciences, Inc.
- Applications of hepatocyte co-culture system24 Sep 2026US 2026/0287577 A1LifeNet Health
Most cited
By later US patents
- Encapsulation of biological material667US 4,352,883 ADamon Corporation · 1982
- Three-dimensional cell and tissue culture system322US 4,963,489 AMarrow-Tech Incorporated · 1990
- Microcapsules containing viable tissue cells318US 4,391,909 ADamon Corporation · 1983
- Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor300US 5,776,748 AChildren's Medical Center Corporation · 1998
- Three-dimensional cell and tissue culture system274US 5,032,508 AMarrow-Tech Incorporated · 1991