C12N 5/0671
Three-dimensional culture, tissue culture or organ culture
Official title: {Three-dimensional culture, tissue culture or organ culture; Encapsulated cells}
C12N5/0671 (Three-dimensional culture, tissue culture or organ culture) appears on 199 US grants and 425 published applications in this corpus.
Search patents in C12N- Granted patents
- 199
- Published applications
- 425
- Assignees
- 233
- Inventors
- 825
- Latest grant
- 1 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 1 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 1 | 0 |
| 1993 | 1 | 0 |
| 1994 | 0 | 0 |
| 1995 | 1 | 0 |
| 1996 | 2 | 0 |
| 1997 | 5 | 0 |
| 1998 | 2 | 0 |
| 1999 | 7 | 0 |
| 2000 | 4 | 0 |
| 2001 | 5 | 2 |
| 2002 | 2 | 3 |
| 2003 | 3 | 9 |
| 2004 | 2 | 6 |
| 2005 | 2 | 10 |
| 2006 | 0 | 1 |
| 2007 | 2 | 14 |
| 2008 | 4 | 13 |
| 2009 | 3 | 3 |
| 2010 | 1 | 9 |
| 2011 | 5 | 8 |
| 2012 | 2 | 14 |
| 2013 | 3 | 15 |
| 2014 | 11 | 13 |
| 2015 | 6 | 7 |
| 2016 | 6 | 21 |
| 2017 | 6 | 21 |
| 2018 | 7 | 15 |
| 2019 | 13 | 26 |
| 2020 | 10 | 33 |
| 2021 | 10 | 28 |
| 2022 | 12 | 39 |
| 2023 | 8 | 30 |
| 2024 | 10 | 27 |
| 2025 | 27 | 36 |
| 2026 | 10 | 22 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Method for producing cell aggregate1 Sep 2026US 12,723,236 B2Osaka University
- Genetically engineered human fetal liver niche as platform for biomanufacturing of hematopoietic stem cells28 Jul 2026US 12,692,479 B2Arizona Board of Regents on behalf of Arizona State University
- Proliferative liver organoid, metabolically activated liver organoid, and use thereof14 Jul 2026US 12,680,080 B2Jsr Corporation
- Encapsulated liver tissue16 Jun 2026US 12,655,392 B2Morphocell Technologies Inc.
- Liver organoid, uses thereof and culture method for obtaining them9 Jun 2026US 12,649,903 B2Koninklijke Nederlandse Akademie van Wetenschappen
- Genetically engineered human fetal liver niche as platform for biomanufacturing of hematopoietic stem cells1 Oct 2026US 2026/0297528 A1Arizona Board of Regents on behalf of Arizona State University
- Liver organoids with intrahepatic sympathetic nerves and methods of use thereof17 Sep 2026US 2026/0275295 A1Children's Hospital Medical Center
- Role of hepatocyte-derived extracellular matrix and coagulation factors for the fate restoration and maintenance of human hepatocytes20 Aug 2026US 2026/0242739 A1Phoenixbio Co., Ltd.
- Composite nanofibrous scaffold enhances in vitro hepatocytes' drug clearance profiles to align with human physiology13 Aug 2026US 2026/0234562 A1University of Maryland, Baltimore County
- Method for producing metabolically activated liver organoid, composition, and method for evaluating test substance2 Jul 2026US 2026/0185054 A1Jsr Corporation
Most cited
By later US patents
- Encapsulation of biological material667US 4,352,883 ADamon Corporation · 1982
- Three-dimensional cell and tissue culture system322US 4,963,489 AMarrow-Tech Incorporated · 1990
- Microcapsules containing viable tissue cells318US 4,391,909 ADamon Corporation · 1983
- Three-dimensional cell and tissue culture system274US 5,032,508 AMarrow-Tech Incorporated · 1991
- Three-dimensional culture of pancreatic parenchymal cells cultured living stromal tissue prepared in vitro220US 6,022,743 AAdvanced Tissue Sciences, Inc. · 2000