C12N 2501/41
Hedgehog proteins
Official title: Hedgehog proteins; Cyclopamine (inhibitor)
C12N2501/41 (Hedgehog proteins) appears on 297 US grants and 610 published applications in this corpus.
Search patents in C12N- Granted patents
- 297
- Published applications
- 610
- Assignees
- 241
- Inventors
- 934
- Latest grant
- 15 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2000 | 1 | 0 |
| 2001 | 1 | 1 |
| 2002 | 0 | 2 |
| 2003 | 1 | 9 |
| 2004 | 2 | 17 |
| 2005 | 2 | 8 |
| 2006 | 2 | 8 |
| 2007 | 2 | 10 |
| 2008 | 3 | 4 |
| 2009 | 6 | 14 |
| 2010 | 4 | 24 |
| 2011 | 4 | 21 |
| 2012 | 6 | 21 |
| 2013 | 11 | 26 |
| 2014 | 16 | 14 |
| 2015 | 15 | 28 |
| 2016 | 16 | 34 |
| 2017 | 16 | 32 |
| 2018 | 26 | 35 |
| 2019 | 30 | 36 |
| 2020 | 22 | 36 |
| 2021 | 13 | 41 |
| 2022 | 19 | 32 |
| 2023 | 20 | 39 |
| 2024 | 22 | 59 |
| 2025 | 22 | 32 |
| 2026 | 15 | 27 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Methods of differentiating neural cells and related compositions and methods of use15 Sep 2026US 12,734,196 B2Aspen Neuroscience, Inc.
- Methods and compositions for generating oligodendrocyte progenitor cells8 Sep 2026US 12,729,368 B2Trailhead Biosystems Inc.
- Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs)7 Jul 2026US 12,674,204 B2The United States of America, as represented by the Secretary, Department of Health and Human Services
- Specification of functional cranial placode derivatives from human pluripotent stem cells5 May 2026US 12,618,044 B2Memorial Sloan Kettering Cancer Center
- Innervated organoid compositions and methods of making same14 Apr 2026US 12,600,943 B2Children's Hospital Medical Center
- Protocol for maturation of 3D engineered heart tissue8 Oct 2026US 2026/0308527 A1
- Human ipsc derived ameloblasts and uses thereof10 Sep 2026US 2026/0265696 A1University of Washington
- Methods and Culture Substrates for Controlled Induction of Biomimetic Neural Tissues Comprising Singular Rosette Structures30 Jul 2026US 2026/0218125 A1Wisconsin Alumni Research Foundation
- Methods and materials for generating stem cell-derived endocrine cell types30 Jul 2026US 2026/0218132 A1Mayo Foundation for Medical Education and Research
- Method for differentiating neural crest stem cells comprising axial specification information16 Jul 2026US 2026/0201324 A1Bless Biotherapeutics Inc.
Most cited
By later US patents
- Endoderm cells from human embryonic stem cells169US 7,326,572 B2Geron Corporation · 2008
- Methods of producing pancreatic hormones165US 7,534,608 B2Cythera, Inc. · 2009
- Islet cells from human embryonic stem cells152US 7,033,831 B2Geron Corporation · 2006
- Methods of producing pancreatic hormones107US 7,695,965 B2Cythera, Inc. · 2010
- Encapsulation of pancreatic cells derived from human pluripotent stem cells105US 8,278,106 B2ViaCyte, Inc. · 2012