C12N 2310/531
Stem-loop
Official title: Stem-loop; Hairpin
C12N2310/531 (Stem-loop) appears on 1,370 US grants and 2,903 published applications in this corpus.
Search patents in C12N- Granted patents
- 1,370
- Published applications
- 2,903
- Assignees
- 1,039
- Inventors
- 5,017
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2000 | 1 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 3 |
| 2004 | 0 | 6 |
| 2005 | 0 | 4 |
| 2006 | 1 | 7 |
| 2007 | 1 | 11 |
| 2008 | 3 | 12 |
| 2009 | 2 | 29 |
| 2010 | 11 | 30 |
| 2011 | 13 | 55 |
| 2012 | 22 | 61 |
| 2013 | 35 | 72 |
| 2014 | 56 | 112 |
| 2015 | 62 | 162 |
| 2016 | 69 | 197 |
| 2017 | 106 | 188 |
| 2018 | 115 | 194 |
| 2019 | 130 | 198 |
| 2020 | 122 | 203 |
| 2021 | 113 | 196 |
| 2022 | 105 | 217 |
| 2023 | 104 | 251 |
| 2024 | 98 | 239 |
| 2025 | 90 | 276 |
| 2026 | 111 | 180 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Gene therapy for neurodegenerative disorders using polynucleotide silencing and replacement6 Oct 2026US 12,753,411 B2The Brigham and Women S Hospital, Inc.
- Methods of activating cells via PTP 1B inhibition29 Sep 2026US 12,746,285 B2Monash University
- Compositions and methods for reprogramming age-restricted non-neuronal cells29 Sep 2026US 12,747,438 B2The Regents of the University of California
- Use of FcgammaRIII inhibitor in preparation of medicament for treating pulmonary fibrosis15 Sep 2026US 12,735,489 B2Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
- Enzymes with RUVC domains15 Sep 2026US 12,735,688 B2Metagenomi Therapeutics, Inc.
- Methods and compositions for microbial delivery of double stranded rna8 Oct 2026US 2026/0305618 A1Rnaissance AG LLC
- Sugar Modified Oligonucleotides and Uses Thereof8 Oct 2026US 2026/0308587 A1Ionis Pharmaceuticals, Inc.
- Nucleic acids encoding crispr-associated proteins and uses thereof8 Oct 2026US 2026/0308602 A1CureVac AG
- Compositions and methods for recombinant aav production8 Oct 2026US 2026/0308620 A1REGENXBIO Inc.
- Methods for treating gastrointestinal inflammatory diseases using alpha-ketoglutarate (akg) modulators1 Oct 2026US 2026/0294856 A1
Most cited
By later US patents
- CRISPR-Cas component systems, methods and compositions for sequence manipulation560US 8,795,965 B2Massachusetts Institute of Technology · 2014
- CRISPR-Cas component systems, methods and compositions for sequence manipulation529US 8,871,445 B2Massachusetts Institute of Technology · 2014
- CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes457US 8,932,814 B2Massachusetts Institute of Technology · 2015
- CRISPR-Cas nickase systems, methods and compositions for sequence manipulation in eukaryotes432US 8,889,356 B2Massachusetts Institute of Technology · 2014
- RNA-directed DNA cleavage by the Cas9-crRNA complex196US 9,637,739 B2Vilnius University · 2017