C12N 15/66
General methods for inserting a gene into a vector to form a
Official title: General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
C12N15/66 (General methods for inserting a gene into a vector to form a) appears on 695 US grants and 1,033 published applications in this corpus.
Search patents in C12N- Granted patents
- 695
- Published applications
- 1,033
- Assignees
- 505
- Inventors
- 1,797
- Latest grant
- 2 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 2 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 5 | 0 |
| 1987 | 8 | 0 |
| 1988 | 5 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 7 | 0 |
| 1992 | 6 | 0 |
| 1993 | 4 | 0 |
| 1994 | 2 | 0 |
| 1995 | 4 | 0 |
| 1996 | 8 | 0 |
| 1997 | 12 | 0 |
| 1998 | 25 | 0 |
| 1999 | 18 | 0 |
| 2000 | 16 | 0 |
| 2001 | 16 | 4 |
| 2002 | 18 | 33 |
| 2003 | 15 | 63 |
| 2004 | 12 | 52 |
| 2005 | 11 | 26 |
| 2006 | 11 | 33 |
| 2007 | 17 | 22 |
| 2008 | 9 | 22 |
| 2009 | 11 | 48 |
| 2010 | 8 | 23 |
| 2011 | 12 | 28 |
| 2012 | 17 | 32 |
| 2013 | 19 | 34 |
| 2014 | 22 | 35 |
| 2015 | 25 | 39 |
| 2016 | 24 | 47 |
| 2017 | 23 | 46 |
| 2018 | 28 | 46 |
| 2019 | 30 | 73 |
| 2020 | 41 | 49 |
| 2021 | 37 | 65 |
| 2022 | 41 | 56 |
| 2023 | 39 | 42 |
| 2024 | 39 | 47 |
| 2025 | 35 | 38 |
| 2026 | 11 | 30 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Methylation-mediated adapter removal on nucleic acid sequences2 Jun 2026US 12,644,115 B2Twist Bioscience Corporation
- Genetically modified rat having PKHD1L1 gene with point mutation and methods for its construction, detection and use19 May 2026US 12,628,802 B2Huashan Hospital Affiliaed To Fudan University
- RNA-guided nucleases and active fragments and variants thereof and methods of use12 May 2026US 12,624,369 B2Life Edit Therapeutics, Inc.
- Compositions and methods for improved gene editing28 Apr 2026US 12,612,619 B2University of Massachusetts
- Genome-wide insulator screening system and use21 Apr 2026US 12,606,820 B2Agricultural Genomics Institute At Shenzhen, Chinese Academy of Agricultural Sciences
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308231 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308232 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same8 Oct 2026US 2026/0308233 A1Regeneron Pharmaceuticals, Inc.
- Anti-vegf protein compositions and methods for producing the same24 Sep 2026US 2026/0285940 A1Regeneron Pharmaceuticals, Inc.
- Rna-guided nucleases and active fragments and variants thereof and methods of use3 Sep 2026US 2026/0258452 A1Life Edit Therapeutics, Inc.
Most cited
By later US patents
- Method of identifying a stochastically-generated peptide, polypeptide, or protein having ligand binding property and compositions thereof519US 5,723,323 A1998
- End-complementary polymerase reaction471US 5,928,905 AAffymetrix, Inc. · 1999
- Indexing linkers384US 5,508,169 AAtomic Energy of Canada Limited · 1996
- Method for the complete chemical synthesis and assembly of genes and genomes364US 6,521,427 B1Egea Biosciences, Inc. · 2003
- Process for the production of stochastically-generated transcription or translation products347US 5,814,476 A1998