C12N 15/635
Externally inducible repressor mediated regulation of gene expression
Official title: {Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline}
C12N15/635 (Externally inducible repressor mediated regulation of gene expression) appears on 390 US grants and 670 published applications in this corpus.
Search patents in C12N- Granted patents
- 390
- Published applications
- 670
- Assignees
- 325
- Inventors
- 1,268
- Latest grant
- 1 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1984 | 1 | 0 |
| 1985 | 1 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 2 | 0 |
| 1994 | 0 | 0 |
| 1995 | 2 | 0 |
| 1996 | 1 | 0 |
| 1997 | 2 | 0 |
| 1998 | 9 | 0 |
| 1999 | 9 | 0 |
| 2000 | 6 | 0 |
| 2001 | 9 | 1 |
| 2002 | 12 | 20 |
| 2003 | 4 | 30 |
| 2004 | 13 | 14 |
| 2005 | 9 | 22 |
| 2006 | 5 | 16 |
| 2007 | 7 | 19 |
| 2008 | 3 | 15 |
| 2009 | 6 | 9 |
| 2010 | 11 | 12 |
| 2011 | 6 | 14 |
| 2012 | 7 | 14 |
| 2013 | 14 | 29 |
| 2014 | 12 | 25 |
| 2015 | 15 | 28 |
| 2016 | 29 | 30 |
| 2017 | 17 | 35 |
| 2018 | 20 | 26 |
| 2019 | 22 | 34 |
| 2020 | 28 | 43 |
| 2021 | 8 | 24 |
| 2022 | 18 | 47 |
| 2023 | 22 | 65 |
| 2024 | 16 | 39 |
| 2025 | 20 | 30 |
| 2026 | 22 | 29 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Enumeration of genetically engineered microorganisms by live cell counting techniques1 Sep 2026US 12,721,882 B2Synlogic Operating Company, Inc.
- Regulated synthetic gene activation systems18 Aug 2026US 12,709,637 B2Trustees of Boston University
- Biosensors for selectively identifying azide ions16 Jun 2026US 12,655,461 B2Rutgers, The State University of New Jersey
- Phosphate sensing microbial gene switch9 Jun 2026US 12,649,699 B2Switch Bioworks, Inc.
- Mutant reverse tetracycline transactivators for expression of genes12 May 2026US 12,624,362 B2President and Fellows of Harvard College
- Means and methods for antibiotic-free propagation of plasmid dna10 Sep 2026US 2026/0265763 A1enGenes Biotech GmbH
- Glucose-regulated gene expression loop control system and use thereof in regulating and controlling blood glucose20 Aug 2026US 2026/0242434 A1East China Normal University
- Inducible Ammonia Production from a Symbiotic Diazotroph, Methods of Creation and Uses Thereof20 Aug 2026US 2026/0242802 A1The Board of Trustees of the Leland Stanford Junior University
- Engineered rnase inhibitor variants30 Jul 2026US 2026/0217777 A1Codexis, Inc.
- Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof30 Jul 2026US 2026/0218165 A1Massachusetts Institute of Technology
Most cited
By later US patents
- Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters186US 5,464,758 A1995
- Methods for regulating gene expression170US 5,814,618 ABASF SE · 1998
- RNA-guided transcriptional regulation127US 9,267,135 B2President and Fellows of Harvard College · 2016
- Tetracycline regulated transcriptional modulators with altered DNA binding specificities102US 5,589,362 ABASF SE · 1996
- Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters99US 5,650,298 ABASF SE · 1997