C07K 16/46
Hybrid immunoglobulins
Official title: Hybrid immunoglobulins (hybrids of an immunoglobulin with a peptide not being an immunoglobulin C07K19/00)
C07K16/46 (Hybrid immunoglobulins) appears on 2,367 US grants and 4,018 published applications in this corpus.
Search patents in C07K- Granted patents
- 2,367
- Published applications
- 4,018
- Assignees
- 1,094
- Inventors
- 5,571
- Latest grant
- 22 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 2 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 2 | 0 |
| 1988 | 1 | 0 |
| 1989 | 3 | 0 |
| 1990 | 6 | 0 |
| 1991 | 2 | 0 |
| 1992 | 5 | 0 |
| 1993 | 11 | 0 |
| 1994 | 3 | 0 |
| 1995 | 5 | 0 |
| 1996 | 21 | 0 |
| 1997 | 29 | 0 |
| 1998 | 32 | 0 |
| 1999 | 40 | 0 |
| 2000 | 29 | 0 |
| 2001 | 36 | 4 |
| 2002 | 18 | 27 |
| 2003 | 22 | 49 |
| 2004 | 19 | 46 |
| 2005 | 12 | 60 |
| 2006 | 20 | 50 |
| 2007 | 12 | 44 |
| 2008 | 22 | 37 |
| 2009 | 25 | 84 |
| 2010 | 41 | 83 |
| 2011 | 36 | 104 |
| 2012 | 59 | 96 |
| 2013 | 69 | 221 |
| 2014 | 88 | 241 |
| 2015 | 111 | 196 |
| 2016 | 142 | 191 |
| 2017 | 145 | 255 |
| 2018 | 114 | 218 |
| 2019 | 140 | 308 |
| 2020 | 156 | 235 |
| 2021 | 161 | 236 |
| 2022 | 160 | 294 |
| 2023 | 151 | 289 |
| 2024 | 168 | 307 |
| 2025 | 164 | 203 |
| 2026 | 84 | 140 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Binding molecules for the treatment of cancer22 Sep 2026US 12,742,022 B2Boehringer Ingelheim International GmbH
- Bispecific antigen binding molecules targeting OX40 and FAP15 Sep 2026US 12,735,485 B2Hoffmann-La Roche Inc.
- Multivalent protein complexes15 Sep 2026US 12,735,486 B2Guangzhou Binding Technologies Co., Limited
- Multi-domain CD1a antagonist/PD-1 agonist antibody molecules15 Sep 2026US 12,735,491 B2Immunocore Limited
- Bispecific anti-human a-beta/human transferrin receptor antibodies and methods of use15 Sep 2026US 12,735,497 B2Hoffmann-La Roche Inc.
- Novel conjugate of immune-stimulating il-2 analog and preparation method thereof8 Oct 2026US 2026/0306646 A1Hanmi Pharm. Co., Ltd.
- Multi-domain molecules8 Oct 2026US 2026/0308260 A1Immunocore Limited
- Il12rb2 binding molecules and methods of use8 Oct 2026US 2026/0308265 A1Synthekine, Inc.
- Anti-nme antibody and method of treating cancer or cancer metastasis8 Oct 2026US 2026/0308282 A1Minerva Biotechnologies Corporation
- Methods and means for the production of ig-like molecules8 Oct 2026US 2026/0308655 A1Merus N.V.
Most cited
By later US patents
- Recombinant immunoglobin preparations4,785US 4,816,567 AGenentech, Inc. · 1989
- Humanized immunoglobulins2,884US 5,585,089 AProtein Design Labs, Inc. · 1996
- Single polypeptide chain binding molecules2,454US 4,946,778 AGenex Corporation · 1990
- Humanized immunoglobulins2,259US 5,530,101 AProtein Design Labs, Inc. · 1996
- Humanized immunoglobulins2,030US 5,693,762 AProtein Design Labs, Inc. · 1997