C07K 14/8146
Metalloprotease inhibitors
Official title: {Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP}
C07K14/8146 (Metalloprotease inhibitors) appears on 112 US grants and 118 published applications in this corpus.
Search patents in C07K- Granted patents
- 112
- Published applications
- 118
- Assignees
- 77
- Inventors
- 239
- Latest grant
- 12 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1984 | 1 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 2 | 0 |
| 1992 | 0 | 0 |
| 1993 | 2 | 0 |
| 1994 | 2 | 0 |
| 1995 | 0 | 0 |
| 1996 | 2 | 0 |
| 1997 | 6 | 0 |
| 1998 | 2 | 0 |
| 1999 | 1 | 0 |
| 2000 | 1 | 0 |
| 2001 | 1 | 0 |
| 2002 | 5 | 10 |
| 2003 | 8 | 8 |
| 2004 | 5 | 9 |
| 2005 | 5 | 9 |
| 2006 | 7 | 9 |
| 2007 | 12 | 9 |
| 2008 | 6 | 1 |
| 2009 | 2 | 3 |
| 2010 | 3 | 5 |
| 2011 | 1 | 4 |
| 2012 | 0 | 3 |
| 2013 | 3 | 1 |
| 2014 | 2 | 3 |
| 2015 | 2 | 1 |
| 2016 | 4 | 8 |
| 2017 | 1 | 4 |
| 2018 | 1 | 1 |
| 2019 | 6 | 4 |
| 2020 | 1 | 4 |
| 2021 | 2 | 7 |
| 2022 | 1 | 3 |
| 2023 | 3 | 2 |
| 2024 | 4 | 6 |
| 2025 | 3 | 2 |
| 2026 | 2 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Assays for TIMP2 having improved performance in biological samples12 May 2026US 12,624,121 B2Biomerieux
- Immunogenic peptide fragments of metalloprotease ADAMTS-7 and uses thereof in anti-atherosclerosis and related diseases14 Apr 2026US 12,599,654 B2Beijing Kimway Biotech Co. Ltd
- Modified anti-inflammatory proteins and method of use11 Nov 2025US 12,466,873 B2James Cook University
- Fused polypeptide with multifunctional activities and use thereof26 Aug 2025US 12,398,196 B2Nanjing Anji Biological Technology Co., Ltd.
- Nano-engineered therapeutic stealth cells8 Apr 2025US 12,270,053 B2Ohio State Innovation Foundation
- Oligonucleotide encoding a tissue inhibitor of metalloproteases protein for medical use in mammals7 May 2026US 2026/0124231 A1
- Caviar polypeptides23 Apr 2026US 2026/0108449 A1
- Nano-engineered therapeutic stealth cells14 Aug 2025US 2025/0257327 A1Ohio State Innovation Foundation
- Protein-based advanced wound healing system24 Jul 2025US 2025/0235516 A1University of South Florida
- Modified anti-inflammatory proteins and method of use5 Dec 2024US 2024/0400649 A1James Cook University
Most cited
By later US patents
- Modified peptides as therapeutic agents359US 6,660,843 B1Amgen Inc. · 2003
- Unique T-lymphocyte line and products derived therefrom94US 4,438,032 AThe Regents of the University of California · 1984
- Therapeutic agents and methods of use thereof for the modulation of angiogenesis88US 6,548,477 B1Praecis Pharmaceuticals, Inc. · 2003
- Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension69US 4,749,688 ASchering Corporation · 1988
- Therapeutic agents and methods of use thereof for the modulation of angiogenesis54US 7,084,108 B2Praecis Pharmaceuticals, Inc. · 2006