Caviar polypeptides
OwnerKenneth Benninginventor
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Abstract
The present invention relates to recombinant, or synthetic caviar polypeptides and methods for their production. The invention also relates to cosmetic products comprising recombinant or synthetic polypeptides of the invention.
Claims27
A composition comprising a recombinant or synthetic caviar polypeptide, wherein the caviar polypeptide is selected from:
- a) a superoxide dismutase (SOD3) polypeptide, wherein the SOD3 polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 1;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 1;
- b) a superoxide dismutase (SOD1) polypeptide, wherein the SOD1 polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 2;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 2;
- c) a tissue inhibitor of metalloproteinase 1 (TIMP1) polypeptide, wherein the TIMP1 polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 3;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 3;
- d) an acidic fibroblast growth factor (aFGF) polypeptide, wherein the aFGF polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 4;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 4;
- e) a basic fibroblast growth factor (bFGF) polypeptide, wherein the bFGF polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 5;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 5;
- f) an insulin-like growth factor 2 (IGF-2) polypeptide, wherein the IGF-2 polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 6;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 6;
- and
- g) a laminin polypeptide, wherein the laminin polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 7;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 7.
The composition according to any one of the preceding claims, wherein the composition comprises a recombinant or synthetic SOD3 polypeptide and a recombinant or synthetic SOD1 polypeptide.
The composition according to any one of the preceding claims, wherein the composition further comprises a recombinant or synthetic stem cell factor (SCF) polypeptide, wherein the SCF polypeptide comprises a polypeptide sequence having:
- (i) at least 70% sequence identity to the amino acid sequence of SEQ ID NO:
- 8;
- or (ii) at least 50 consecutive amino acids of SEQ ID NO:
- 8.
The composition according to any one of the preceding claims, wherein the composition comprises a recombinant or synthetic SOD3 polypeptide, a recombinant or synthetic SOD1 polypeptide, and a recombinant or synthetic SCF polypeptide.
The composition according to any one of the preceding claims, wherein one or more of the recombinant or synthetic polypeptides comprise a purification tag, such as a His-tag.
The composition according to any one of the preceding claims, wherein the composition further comprises collagen.
The composition according to any one of the preceding claims, wherein the composition is a cosmetic composition.
Dependencies are inferred from the claim text.