C07D 499/21
Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a
Official title: with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
C07D499/21 (Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a) appears on 70 US grants and 45 published applications in this corpus.
Search patents in C07D- Granted patents
- 70
- Published applications
- 45
- Assignees
- 60
- Inventors
- 190
- Latest grant
- 26 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 21 | 0 |
| 1977 | 3 | 0 |
| 1978 | 5 | 0 |
| 1979 | 2 | 0 |
| 1980 | 1 | 0 |
| 1981 | 1 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 4 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 1 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 0 | 0 |
| 1996 | 0 | 0 |
| 1997 | 0 | 0 |
| 1998 | 0 | 0 |
| 1999 | 0 | 0 |
| 2000 | 0 | 0 |
| 2001 | 0 | 0 |
| 2002 | 0 | 0 |
| 2003 | 0 | 0 |
| 2004 | 0 | 0 |
| 2005 | 0 | 0 |
| 2006 | 0 | 0 |
| 2007 | 0 | 2 |
| 2008 | 0 | 1 |
| 2009 | 0 | 3 |
| 2010 | 0 | 2 |
| 2011 | 0 | 1 |
| 2012 | 2 | 1 |
| 2013 | 1 | 0 |
| 2014 | 1 | 1 |
| 2015 | 0 | 2 |
| 2016 | 2 | 4 |
| 2017 | 3 | 2 |
| 2018 | 3 | 4 |
| 2019 | 2 | 3 |
| 2020 | 4 | 3 |
| 2021 | 1 | 5 |
| 2022 | 2 | 2 |
| 2023 | 2 | 2 |
| 2024 | 0 | 4 |
| 2025 | 7 | 2 |
| 2026 | 2 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C07D 499/44Compounds with an amino radical acylated by carboxylic acids, attached in position44
- C07D 499/80Compounds with a nitrogen-containing hetero ring, attached with the ring nitrogen atom5
- C07D 499/22Salts with organic bases4
- C07D 499/28With modified 2-carboxyl group4
- C07D 499/42Compounds with a free primary amino radical attached in position 64
- C07D 499/78Compounds with an amino radical, acylated by carbonic acid, or by nitrogen3
Recent patents
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- Method for separating amoxicillin and phenylacetic acid from reaction solution in one-step enzymatic synthesis of amoxicillin2 Sep 2025US 12,404,534 B1Xingzhi College Zhejiang Normal University
- Fluorescence quenching immunoassay1 Jul 2025US 12,345,641 B2IDEZZ Laboratories, Inc.
- Method for producing ß-lactam compound17 Sep 2026US 2026/0274862 A1FUJIFILM Corporation
- Mutual Prodrugs of Cromoglicic Acid28 Aug 2025US 2025/0269041 A1Samdolite Pharmaceuticals, Inc.
- Platform drug delivery system utilizing crystal engineering and theanine dissolution17 Jul 2025US 2025/0228778 A1Theaprin Pharmaceuticals Inc.
- Mercaptoacetophenone aminohydrazones, their salts and uses thereof21 Nov 2024US 2024/0383846 A1London Pharmaceuticals and Research Corporation
- Metallo-ß-lactamase inhibitors10 Oct 2024US 2024/0335453 A1
Most cited
By later US patents
- Cephalosporin and pharmaceutical preparations containing the same16US 3,935,204 AAstra Lakemedel Aktiebolag · 1976
- Ampicillin derivatives substituted by heterocyclic acyl group14US 3,953,428 AYamanouchi Pharmaceutical Co., Ltd. · 1976
- Ureidoacetamido-penicillins14US 3,959,258 ABayer Aktiengesellschaft · 1976
- 7[2(Substituted phenyl)2-(amino)acetamido]cephalosporin derivatives14US 4,162,314 AMerck Patent GmbH · 1979
- Production of amoxicillin13US 3,980,637 ABristol-Myers Company · 1976