C07D 241/34
Guanidines
Official title: (Amino-pyrazine carbonamido) guanidines
C07D241/34 (Guanidines) appears on 16 US grants and 25 published applications in this corpus.
Search patents in C07D- Granted patents
- 16
- Published applications
- 25
- Assignees
- 8
- Inventors
- 31
- Latest grant
- 14 Feb 2023
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 2005 | 0 | 2 |
| 2006 | 0 | 0 |
| 2007 | 0 | 0 |
| 2008 | 1 | 0 |
| 2009 | 0 | 0 |
| 2010 | 0 | 0 |
| 2011 | 0 | 0 |
| 2012 | 0 | 1 |
| 2013 | 0 | 4 |
| 2014 | 3 | 2 |
| 2015 | 3 | 4 |
| 2016 | 1 | 2 |
| 2017 | 2 | 2 |
| 2018 | 1 | 1 |
| 2019 | 1 | 1 |
| 2020 | 2 | 0 |
| 2021 | 1 | 1 |
| 2022 | 0 | 0 |
| 2023 | 1 | 0 |
| 2024 | 0 | 1 |
| 2025 | 0 | 4 |
By publication year.
Recent patents
- 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide14 Feb 2023US 11,578,042 B2Parion Sciences, Inc.
- Antiviral compounds and methods7 Dec 2021US 11,192,863 B2Biotron Limited
- 3,5-diamino-6-chloro-N—(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide25 Aug 2020US 10,752,597 B2Parion Sciences, Inc.
- Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases7 Jan 2020US 10,526,292 B2Parion Sciences, Inc.
- Antiviral compounds and methods12 Nov 2019US 10,472,332 B2Biotron Limited
- Compositions for and methods of modulating rna stability11 Sep 2025US 2025/0282714 A1Duke University
- Compositions for and methods of modulating rna stability28 Aug 2025US 2025/0270165 A1Duke University
- Biphenyl-substituted epithelial sodium channel blocking compounds10 Apr 2025US 2025/0115561 A1Parion Sciences, Inc.
- Bicyclic-substituted epithelial sodium channel blocking compounds3 Apr 2025US 2025/0109110 A1Parion Sciences, Inc.
- Amiloride derivatives and methods of using same for the treatment of viral infections11 Apr 2024US 2024/0116879 A1Case Western Reserve University
Most cited
By later US patents
- Alaphatic pyrazinoylguanidine sodium channel blockers41US 7,375,107 B2Parion Sciences, Inc. · 2008
- 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide24US 8,669,262 B2Parion Sciences, Inc. · 2014
- Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases18US 8,980,898 B2Parion Sciences, Inc. · 2015
- Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases10US 9,260,398 B2Parion Sciences, Inc. · 2016
- 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide7US 9,586,910 B2Parion Sciences, Inc. · 2017