C07D 217/02
Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems: with only hydrogen
Official title: with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
C07D217/02 (Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems: with only hydrogen) appears on 1,416 US grants and 1,435 published applications in this corpus.
Search patents in C07D- Granted patents
- 1,416
- Published applications
- 1,435
- Assignees
- 734
- Inventors
- 5,004
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 13 | 0 |
| 1977 | 15 | 0 |
| 1978 | 9 | 0 |
| 1979 | 6 | 0 |
| 1980 | 15 | 0 |
| 1981 | 12 | 0 |
| 1982 | 13 | 0 |
| 1983 | 6 | 0 |
| 1984 | 10 | 0 |
| 1985 | 10 | 0 |
| 1986 | 6 | 0 |
| 1987 | 12 | 0 |
| 1988 | 9 | 0 |
| 1989 | 23 | 0 |
| 1990 | 15 | 0 |
| 1991 | 11 | 0 |
| 1992 | 12 | 0 |
| 1993 | 16 | 0 |
| 1994 | 17 | 0 |
| 1995 | 23 | 0 |
| 1996 | 33 | 0 |
| 1997 | 13 | 0 |
| 1998 | 36 | 0 |
| 1999 | 30 | 0 |
| 2000 | 26 | 0 |
| 2001 | 38 | 9 |
| 2002 | 31 | 24 |
| 2003 | 37 | 69 |
| 2004 | 29 | 75 |
| 2005 | 33 | 91 |
| 2006 | 40 | 63 |
| 2007 | 47 | 66 |
| 2008 | 40 | 71 |
| 2009 | 50 | 73 |
| 2010 | 42 | 89 |
| 2011 | 44 | 53 |
| 2012 | 60 | 50 |
| 2013 | 52 | 51 |
| 2014 | 64 | 64 |
| 2015 | 55 | 79 |
| 2016 | 41 | 49 |
| 2017 | 43 | 56 |
| 2018 | 41 | 47 |
| 2019 | 39 | 52 |
| 2020 | 33 | 57 |
| 2021 | 38 | 48 |
| 2022 | 38 | 40 |
| 2023 | 24 | 62 |
| 2024 | 17 | 42 |
| 2025 | 28 | 37 |
| 2026 | 21 | 18 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- NAMPT modulators29 Sep 2026US 12,747,203 B2Cytokinetics, Inc.
- Tetrahydroisoquinoline compound as potassium channel modulator and preparation and application thereof11 Aug 2026US 12,703,687 B2Shanghai Zhimeng Biopharma, Inc.
- Rock inhibitors and uses thereof28 Jul 2026US 12,692,234 B2Alcon Inc.
- Method of inhibiting tau phosphorylation7 Jul 2026US 12,674,134 B2Filana Therapeutics, Inc.
- Method of inhibiting tau phosphorylation23 Jun 2026US 12,662,658 B2Filana Therapeutics, Inc.
- Rock inhibitors and uses thereof1 Oct 2026US 2026/0297033 A1Alcon Inc.
- Compositions comprising inhibitors of microsomal triglyceride transfer protein and apo-b secretion20 Aug 2026US 2026/0240833 A1Redux Therapeutics, LLC
- Compounds and methods for treating protein aggregation diseases20 Aug 2026US 2026/0242340 A1Acelot, Inc.
- Mlh1 selective (series 1b) compounds30 Jul 2026US 2026/0217687 A1NeoPhore Limited
- Crystalline polymorph forms of a trpv1 antagonist and formulations thereof9 Jul 2026US 2026/0193188 A1Bausch + Lomb Ireland Limited
Most cited
By later US patents
- Color-safe bleach boosters, compositions and laundry methods employing same297US 5,576,282 AThe Procter & Gamble Company · 1996
- Modulators of ATP-binding cassette transporters157US 7,495,103 B2Vertex Pharmaceuticals Incorporated · 2009
- Urea derivatives and their use as ACAT inhibitors134US 5,621,010 ANisshin Flour Milling Co., Ltd. · 1997
- Modulators of ATP-binding cassette transporters105US 8,101,767 B2Vertex Pharmaceuticals Incorporated · 2012
- Modulators of ATP-binding cassette transporters97US 8,324,242 B2Vertex Pharmaceutical Incorporated · 2012