Rock inhibitors and uses thereof
AssigneeAlcon Inc.
InventorsCasey Casimir Kopczynski, Jill Marie Sturdivant, Michael Scott McClure, Anjali Biren Joshi
Life of this patent
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Abstract
Provided herein are compounds comprising a formula of 4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl adamantane carboxylate (e.g., compounds of formula (I) or formula (II)) or a pharmaceutically acceptable salt thereof. The compounds are useful for reducing intraocular pressure and for treating glaucoma or ocular hypertension.
Claims21
1-46. (canceled)
A method of reducing intraocular pressure in a subject in need thereof, comprising administration of a compound to an eye of the subject, wherein the compound has a formula:
- or a pharmaceutically acceptable salt thereof.
49-51. (canceled)
A method of treating glaucoma in a subject in need thereof, comprising administration of a compound to an eye of the subject, wherein the compound has a formula:
- or a pharmaceutically acceptable salt thereof.
A method of treating ocular hypertension in a subject in need thereof, comprising administration of a compound to an eye of the subject, wherein the compound has a formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.