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US 7,495,103 B2Granted
Modulators of ATP-binding cassette transporters
AssigneeVertex Pharmaceuticals Incorporated
InventorsSara Hadida-Ruah, Anna Hazelwood, Peter Grootenhuis, Fred Van Goor, Ashvani Singh, Jinglan Zhou, Jason McCartney
Life of this patent
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Abstract
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Claims2
A compound:
- N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide,
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.