A61L 33/0076
Chemical modification of the substrate
Official title: {Chemical modification of the substrate}
A61L33/0076 (Chemical modification of the substrate) appears on 227 US grants and 152 published applications in this corpus.
Search patents in A61L- Granted patents
- 227
- Published applications
- 152
- Assignees
- 133
- Inventors
- 467
- Latest grant
- 31 Mar 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 0 | 0 |
| 1978 | 1 | 0 |
| 1979 | 0 | 0 |
| 1980 | 2 | 0 |
| 1981 | 0 | 0 |
| 1982 | 1 | 0 |
| 1983 | 2 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 2 | 0 |
| 1987 | 3 | 0 |
| 1988 | 4 | 0 |
| 1989 | 3 | 0 |
| 1990 | 5 | 0 |
| 1991 | 6 | 0 |
| 1992 | 10 | 0 |
| 1993 | 11 | 0 |
| 1994 | 11 | 0 |
| 1995 | 7 | 0 |
| 1996 | 4 | 0 |
| 1997 | 8 | 0 |
| 1998 | 11 | 0 |
| 1999 | 10 | 0 |
| 2000 | 13 | 0 |
| 2001 | 8 | 2 |
| 2002 | 7 | 7 |
| 2003 | 11 | 10 |
| 2004 | 4 | 11 |
| 2005 | 3 | 7 |
| 2006 | 6 | 6 |
| 2007 | 3 | 9 |
| 2008 | 4 | 3 |
| 2009 | 1 | 3 |
| 2010 | 3 | 4 |
| 2011 | 0 | 7 |
| 2012 | 5 | 3 |
| 2013 | 3 | 3 |
| 2014 | 2 | 6 |
| 2015 | 5 | 8 |
| 2016 | 5 | 10 |
| 2017 | 5 | 9 |
| 2018 | 6 | 6 |
| 2019 | 4 | 6 |
| 2020 | 5 | 7 |
| 2021 | 6 | 2 |
| 2022 | 8 | 4 |
| 2023 | 2 | 5 |
| 2024 | 3 | 7 |
| 2025 | 2 | 3 |
| 2026 | 1 | 4 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Valve material with combined anti-clotting and anti-calcification properties and preparation method31 Mar 2026US 12,589,187 B2Jilin Venus Haoyue Medical Limited
- Anti-thrombogenic medical devices and methods8 Apr 2025US 12,268,617 B2Covidien LP
- High anticoagulation ECMO and extracorporeal circulation consumable14 Jan 2025US 12,194,220 B2Wenzhou Safety (Emergency) Research Institute, Tianjin University
- Coating compositions, polymeric coatings, and methods23 Jul 2024US 12,042,580 B2Covalon Technologies Inc.
- Processes for immobilising biological entities25 Jun 2024US 12,016,978 B2Carmeda AB
- Heparin-functionalized surface, method for its preparation and use thereof20 Aug 2026US 2026/0241080 A1
- Fibrin compositions, substrates thereof, and methods of making thereof25 Jun 2026US 2026/0174937 A1
- Nanostructured low-immunogenic biological artificial blood vessel and preparation method therefor7 May 2026US 2026/0124342 A1Humatrix Medical Technology (Suzhou) Co., Ltd.
- Medical device and method for manufacturing the same16 Apr 2026US 2026/0102544 A1Terumo Kabushiki Kaisha
- Multifunctional Surface Modification of Biomaterials to Reduce Thrombosis23 Oct 2025US 2025/0325733 A1
Most cited
By later US patents
- Vascular prosthesis having fluorinated coating with varying F/C ratio464US 4,718,907 AAtrium Medical Corporation · 1988
- Process for producing hydroxylated plasma-polymerized films and the use of the films for enhancing the compatiblity of biomedical implants432US 5,112,457 ACase Western Reserve University · 1992
- Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like367US 6,387,379 B1University of Florida · 2002
- Negatively charged polymeric electret implant306US 5,759,205 ABrown University Research Foundation · 1998
- Medical device with biomolecule-coated surface graft matrix281US 5,866,113 AMedtronic, Inc. · 1999