A61K 38/4886
Metalloendopeptidases
Official title: {Metalloendopeptidases (3.4.24), e.g. collagenase}
A61K38/4886 (Metalloendopeptidases) appears on 1,185 US grants and 2,089 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,185
- Published applications
- 2,089
- Assignees
- 593
- Inventors
- 2,065
- Latest grant
- 18 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1979 | 1 | 0 |
| 1980 | 0 | 0 |
| 1981 | 0 | 0 |
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 1 | 0 |
| 1985 | 1 | 0 |
| 1986 | 0 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 0 | 0 |
| 1991 | 2 | 0 |
| 1992 | 3 | 0 |
| 1993 | 3 | 0 |
| 1994 | 2 | 0 |
| 1995 | 6 | 0 |
| 1996 | 4 | 0 |
| 1997 | 2 | 0 |
| 1998 | 8 | 0 |
| 1999 | 6 | 0 |
| 2000 | 12 | 0 |
| 2001 | 14 | 13 |
| 2002 | 28 | 42 |
| 2003 | 20 | 34 |
| 2004 | 13 | 71 |
| 2005 | 21 | 75 |
| 2006 | 21 | 67 |
| 2007 | 27 | 73 |
| 2008 | 37 | 74 |
| 2009 | 19 | 76 |
| 2010 | 43 | 93 |
| 2011 | 35 | 81 |
| 2012 | 45 | 99 |
| 2013 | 68 | 78 |
| 2014 | 76 | 104 |
| 2015 | 74 | 93 |
| 2016 | 72 | 103 |
| 2017 | 65 | 102 |
| 2018 | 72 | 82 |
| 2019 | 63 | 106 |
| 2020 | 59 | 95 |
| 2021 | 65 | 99 |
| 2022 | 44 | 86 |
| 2023 | 40 | 108 |
| 2024 | 48 | 95 |
| 2025 | 41 | 82 |
| 2026 | 22 | 58 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Treatment of brain damage18 Aug 2026US 12,708,661 B2Ipsen Biopharm Ltd.
- Use of clostridium histolyticum protease mixture in promoting wound healing4 Aug 2026US 12,697,374 B2Smith & Nephew, Inc.
- Treatment of chronic obstructive pulmonary disease using botulinum toxin4 Aug 2026US 12,697,375 B2Penland Foundation
- Methods of reducing collagenase-mediated bruising in a subject having cellulite30 Jun 2026US 12,667,607 B2Endo Operations Limited
- ADAMTS13 treatment to enhance graft survival23 Jun 2026US 12,661,390 B2Children's Medical Center Corporation
- Stabilized liquid and lyophilized adamts13 formulations8 Oct 2026US 2026/0306593 A1Takeda Pharmaceutical Company Limited
- Lifting agent with therapeutics8 Oct 2026US 2026/0306594 A1Boston Scientific Scimed, Inc.
- Zonal and targeted methods and uses for treating pain, inflammation, stiffness and arthrofibrosis and balancing muscle forces after total knee arthroplasty (tka)8 Oct 2026US 2026/0306595 A1
- Treatment of pain8 Oct 2026US 2026/0306596 A1Ipsen Biopharm Ltd.
- Methods Of Treating Plantar Fibromatosis1 Oct 2026US 2026/0295023 A1
Most cited
By later US patents
- Biodegradable botulinum toxin implant657US 6,506,399 B2Allergan Sales, Inc. · 2003
- Neurotoxin implant376US 6,306,423 B1Allergan Sales, Inc. · 2001
- Treatment of autonomic nerve dysfunction with botulinum toxin359US 5,766,605 AMount Sinai School of Medicine of the City University of New York · 1998
- Clostridial toxin derivatives able to modify peripheral sensory afferent functions318US 5,989,545 AMicrobiological Research Authority · 1999
- Frozen piercing implements and methods for piercing a substrate284US 8,784,385 B2The Invention Science Fund I, LLC · 2014