Treatment of chronic obstructive pulmonary disease using botulinum toxin
AssigneePenland Foundation
InventorRoland M. Williams
Life of this patent
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Abstract
Botulinum toxin for use in treating chronic obstructive pulmonary disease (COPD) in a patient in need thereof is provided. The treatment comprises administering botulinum toxin to the patient. The botulinum toxin may be administered by subcutaneous or intradermal injection. The subcutaneous or intradermal injection may be administered to and/or around the vicinity of a trigeminal nerve, a cervical nerve, a thoracic nerve, a lumbar nerve, and/or a sacral nerve of the patient.
Claims20
A method for treating chronic obstructive pulmonary disease (COPD) in a patient in need thereof, the method comprising administering botulinum toxin to the patient, thereby treating COPD, wherein administering for an adult comprises, by subcutaneous or intradermal injection, 1-4 units to and/or around the vicinity of a trigeminal nerve, 1-4 units to and/or around the vicinity of a cervical nerve, lateral to the patient's spine, 1-4 units to and/or around the vicinity of a thoracic nerve, lateral to the patient's spine, 1-4 units to and/or around the vicinity of a lumbar nerve, lateral to the patient's spine, and/or 1-4 units to and/or around the vicinity of a sacral nerve, lateral to the patient's spine, and monitoring whether the patient's blood level of at least one neuroexcitatory substance selected from substance P, CGRP, and glutamate normalizes.
Dependencies are inferred from the claim text.