A61K 31/496
Non-condensed piperazines containing further heterocyclic rings
Official title: Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K31/496 (Non-condensed piperazines containing further heterocyclic rings) appears on 6,031 US grants and 11,433 published applications in this corpus.
Search patents in A61K- Granted patents
- 6,031
- Published applications
- 11,433
- Assignees
- 3,469
- Inventors
- 22,398
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 3 | 0 |
| 1977 | 0 | 0 |
| 1978 | 1 | 0 |
| 1979 | 2 | 0 |
| 1980 | 0 | 0 |
| 1981 | 1 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 2 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 7 | 0 |
| 1994 | 3 | 0 |
| 1995 | 7 | 0 |
| 1996 | 20 | 0 |
| 1997 | 43 | 0 |
| 1998 | 50 | 0 |
| 1999 | 45 | 0 |
| 2000 | 59 | 0 |
| 2001 | 57 | 27 |
| 2002 | 78 | 136 |
| 2003 | 84 | 229 |
| 2004 | 77 | 248 |
| 2005 | 63 | 236 |
| 2006 | 119 | 251 |
| 2007 | 61 | 225 |
| 2008 | 88 | 222 |
| 2009 | 76 | 248 |
| 2010 | 98 | 284 |
| 2011 | 125 | 317 |
| 2012 | 157 | 316 |
| 2013 | 230 | 482 |
| 2014 | 309 | 585 |
| 2015 | 403 | 665 |
| 2016 | 374 | 649 |
| 2017 | 442 | 613 |
| 2018 | 418 | 585 |
| 2019 | 452 | 639 |
| 2020 | 361 | 632 |
| 2021 | 342 | 588 |
| 2022 | 293 | 655 |
| 2023 | 262 | 629 |
| 2024 | 298 | 694 |
| 2025 | 306 | 706 |
| 2026 | 212 | 572 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- PHD inhibitor compounds, compositions, and use6 Oct 2026US 12,753,161 B2Akebia Therapeutics, Inc.
- Salt containing piperazine polycyclic derivative, crystal form thereof, preparation method therefor, and use thereof6 Oct 2026US 12,753,166 B2Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
- Amido-substituted pyridyl compounds and methods of use thereof for the treatment of herpesviruses6 Oct 2026US 12,753,187 B2Merck Sharp & Dohme Corp.
- Nanosuspension formulation for treatment of pulmonary fibrosis29 Sep 2026US 12,746,210 B2Federal University of Rio De Janeiro
- Crystallization process of aripiprazole derivatives in extended release formulations for treatment of schizophrenia29 Sep 2026US 12,746,237 B2Alkermes Pharma Ireland Limited
- Drug-polymer amorphous solid dispersions using linear polyacrylic acid polymers8 Oct 2026US 2026/0306410 A1Lubrizol Advanced Materials, Inc.
- Composition for removing and inhibiting senescent cells, and uses thereof8 Oct 2026US 2026/0306460 A1Lifeceutix Co., Ltd.
- Inverse agonists of rar related orphan receptors (rors)8 Oct 2026US 2026/0306484 A111949098 CANADA INC. (NUREDCO) c/o Jean I. TCHERVENKOV
- Compositions and methods for the treatment of congenital adrenal hyperplasia8 Oct 2026US 2026/0306485 A1Crinetics Pharmaceuticals, Inc.
- Combination therapy with clk/dyrk inhibitors and bcl2 inhibitors to treat leukemia8 Oct 2026US 2026/0306486 A1BioSplice Therapeutics, Inc.
Most cited
By later US patents
- Solid carriers for improved delivery of active ingredients in pharmaceutical compositions930US 6,248,363 B1Lipocine Inc. · 2001
- Solid carriers for improved delivery of active ingredients in pharmaceutical compositions684US 6,923,988 B2Lipocine Inc. · 2005
- Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions616US 6,569,463 B2Lipocine Inc. · 2003
- Pharmaceutical and cosmetic carrier or composition for topical application284US 6,911,211 B2Foamix Ltd. · 2005
- Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth243US 6,861,053 B1Cedars-Sinai Medical Center · 2005