Amido-substituted pyridyl compounds and methods of use thereof for the treatment of herpesviruses

A compound of formula (I):

• or a pharmaceutically acceptable salt thereof,
• wherein:
• R1 is —O-(5 or 6-membered monocyclic heterocycloalkyl), or —O-(9 or 10-membered bicyclic heterocycloalkyl), wherein said 5 or 6-membered monocyclic heterocycloalkyl group, and said 9 or 10-membered bicyclic heterocycloalkyl group, may each be optionally substituted with one or more RA groups, which can be the same or different;
• R2 is selected from H, C1-C6 alkyl, C1-C6 hydroxyalkyl, —(C1-C6 alkylene)m-N(R4)2, C3-C6 monocyclic cycloalkyl, 6 to 10-membered bicyclic cycloalkyl, 3 to 7-membered monocyclic heterocycloalkyl, 6 to 10-membered bicyclic heterocycloalkyl, —(C1-C6 alkylene)m-(5 or 6-membered monocyclic heteroaryl), and 9 or 10-membered bicyclic heteroaryl, wherein said C3-C6 monocyclic cycloalkyl group, said 6 to 10-membered bicyclic cycloalkyl group, said 3 to 7-membered monocyclic heterocycloalkyl group, said 6 to 10-membered bicyclic heterocycloalkyl group, said 5 or 6-membered monocyclic heteroaryl group, and said 9 or 10-membered bicyclic heteroaryl group may each be optionally substituted with one or more RB groups, which can be the same or different, or R2 is:
• R3 is —O—(C1-C6 alkyl), —(C1-C6 alkylene)-O—(C1-C6 alkyl), —O—(C1-C6 hydroxyalkyl), —O—(C1-C6 cyanoalkyl), —O—(C1-C6 alkylene)-(C3-C7 cycloalkyl), —O—(C1-C6 alkylene)-N(R4)2, —O—(C1-C6 alkylene)-C(O)N(R4)2, —O—(C1-C6 haloalkyl), —O—(C1-C6 alkylene)-(3 to 7-membered monocyclic heterocycloalkyl), —O—(C1-C6 alkylene)-(5 or 6-membered monocyclic heteroaryl), wherein said 3 to 7-membered monocyclic heterocycloalkyl group, said 5 or 6-membered monocyclic heteroaryl group, and said 3 to 7 membered cycloalkyl group may each be optionally substituted with one or more RD groups, which can be the same or different;
• each occurrence of R4 is independently H or C1-C6 alkyl;
• R5 is phenyl, which may be optionally substituted with one or more RC groups, which can be the same or different;
• each occurrence of RA is independently selected from C1-C6 alkyl, oxo, and —C(O)—C1-C6 alkyl;
• each occurrence of RB is independently selected from C1-C6 alkyl, —O—(C1-C6 alkyl), —OH, oxo, halo, —C(O)H, C1-C6 haloalkyl, C1-C6 hydroxyalkyl, C3-C6 monocyclic cycloalkyl, —(C1-C6 alkylene)m-(5 or 6-membered monocyclic heteroaryl), —(C1-C6 alkylene)m-N(R4)2, —(C1-C6 alkylene)m-C(O)N(R4)2, and —(C1-C6 alkylene)-O—(C1-C6 alkyl);
• RC represents up to 3 one or more optional phenyl group substituents, which can be the same or different, and are each independently selected from C1-C6 alkyl, halo, —C1-C6 haloalkyl, and —CN;
• each occurrence of RD is independently selected from C1-C6 alkyl, oxo, halo, —C1-C6 haloalkyl, and —CN;
• and
• each occurrence of m is independently 0 or 1.