A61K 31/436
The heterocyclic ring system containing a six-membered ring having oxygen as a
Official title: the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61K31/436 (The heterocyclic ring system containing a six-membered ring having oxygen as a) appears on 1,613 US grants and 3,345 published applications in this corpus.
Search patents in A61K- Granted patents
- 1,613
- Published applications
- 3,345
- Assignees
- 1,129
- Inventors
- 5,158
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1994 | 1 | 0 |
| 1995 | 0 | 0 |
| 1996 | 10 | 0 |
| 1997 | 9 | 0 |
| 1998 | 5 | 0 |
| 1999 | 11 | 0 |
| 2000 | 6 | 0 |
| 2001 | 13 | 6 |
| 2002 | 15 | 24 |
| 2003 | 13 | 32 |
| 2004 | 9 | 36 |
| 2005 | 8 | 35 |
| 2006 | 13 | 57 |
| 2007 | 9 | 50 |
| 2008 | 3 | 70 |
| 2009 | 11 | 66 |
| 2010 | 21 | 92 |
| 2011 | 14 | 105 |
| 2012 | 30 | 96 |
| 2013 | 79 | 150 |
| 2014 | 75 | 175 |
| 2015 | 92 | 177 |
| 2016 | 103 | 223 |
| 2017 | 123 | 192 |
| 2018 | 110 | 196 |
| 2019 | 130 | 207 |
| 2020 | 116 | 222 |
| 2021 | 122 | 221 |
| 2022 | 108 | 217 |
| 2023 | 84 | 215 |
| 2024 | 106 | 189 |
| 2025 | 97 | 176 |
| 2026 | 67 | 116 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Neo-Islets comprising stem and islet cells and treatment of diabetes mellitus therewith6 Oct 2026US 12,753,392 B2SymbioCellTech, LLC
- Rapamycin-containing pharmaceutical composition22 Sep 2026US 12,740,970 B2Nobelpharma AB
- Polymer-encapsulated drug particles1 Sep 2026US 12,721,816 B2Tonic Medical, Inc.
- Bacterial DNA gyrase inhibitors and methods of use thereof25 Aug 2026US 12,714,692 B2The Florida International University Board of Trustees
- Compositions and methods for treating or preventing dermal disorders25 Aug 2026US 12,714,698 B2Drexel University
- Combination therapy for pulmonary hypertension8 Oct 2026US 2026/0306461 A1Vivus, Inc.
- Oxadiazolyl dihydropyrano[2,3-b]pyridine inhibitors of hipk2 for treating kidney fibrosis8 Oct 2026US 2026/0308166 A1Icahn School of Medicine at Mount Sinai
- Compositions and methods using thymol and/or carvacrol for induction of autophagy1 Oct 2026US 2026/0294840 A1Societe des Produits Nestle S. A.
- Methods for treating gastrointestinal inflammatory diseases using alpha-ketoglutarate (akg) modulators1 Oct 2026US 2026/0294856 A1
- Injectable, sustained-release microsphere formulations containing rapamycin and/or rapamycin analogs and methods of making and using the formulations1 Oct 2026US 2026/0294877 A1Texas Animal Health Innovations LLC
Most cited
By later US patents
- Polymer compositions containing bioactive agents and methods for their use299US 6,770,729 B2Medtronic MiniMed, Inc. · 2004
- Coatings for medical devices285US 6,746,773 B2Ethicon, Inc. · 2004
- Method of treating restenosis with rapamycin259US 5,516,781 AAmerican Home Products Corporation · 1996
- Oleaginous pharmaceutical and cosmetic foam202US 7,820,145 B2Foamix Ltd. · 2010
- Antiinflammatory drug and delivery device188US 6,776,796 B2Cordis Corportation · 2004