Compositions and methods for treating or preventing dermal disorders
AssigneeDrexel University
InventorsChristian Sell, Timothy Nacarelli, Ashley Azar
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Abstract
The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
Claims5
A method of increasing the lifespan, preserving cell organization, or preventing or minimizing senescence of a mammalian dermal fibroblast, the method comprising:
- contacting the dermal fibroblast with a topical composition comprising about 0.001-0.01% (w/w) of a mTORC1 inhibitor or a salt, solvate, enantiomer or diastereoisomer thereof.
Dependencies are inferred from the claim text.