C12N 15/625
Containing a sequence coding for a signal sequence
Official title: {containing a sequence coding for a signal sequence}
C12N15/625 (Containing a sequence coding for a signal sequence) appears on 502 US grants and 615 published applications in this corpus.
Search patents in C12N- Granted patents
- 502
- Published applications
- 615
- Assignees
- 457
- Inventors
- 1,849
- Latest grant
- 22 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1982 | 1 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 3 | 0 |
| 1987 | 2 | 0 |
| 1988 | 4 | 0 |
| 1989 | 7 | 0 |
| 1990 | 9 | 0 |
| 1991 | 17 | 0 |
| 1992 | 14 | 0 |
| 1993 | 15 | 0 |
| 1994 | 12 | 0 |
| 1995 | 13 | 0 |
| 1996 | 19 | 0 |
| 1997 | 15 | 0 |
| 1998 | 29 | 0 |
| 1999 | 20 | 0 |
| 2000 | 12 | 0 |
| 2001 | 8 | 2 |
| 2002 | 10 | 21 |
| 2003 | 19 | 23 |
| 2004 | 8 | 17 |
| 2005 | 6 | 13 |
| 2006 | 7 | 13 |
| 2007 | 8 | 9 |
| 2008 | 9 | 12 |
| 2009 | 8 | 12 |
| 2010 | 6 | 15 |
| 2011 | 13 | 19 |
| 2012 | 11 | 9 |
| 2013 | 8 | 15 |
| 2014 | 8 | 16 |
| 2015 | 12 | 12 |
| 2016 | 9 | 16 |
| 2017 | 16 | 22 |
| 2018 | 9 | 26 |
| 2019 | 17 | 28 |
| 2020 | 9 | 20 |
| 2021 | 23 | 25 |
| 2022 | 16 | 107 |
| 2023 | 11 | 73 |
| 2024 | 13 | 16 |
| 2025 | 22 | 33 |
| 2026 | 24 | 41 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Chimeric antigen receptors to HER2 and methods of use thereof22 Sep 2026US 12,742,020 B2BioAtla, Inc.
- Integration of nucleic acid constructs into eukaryotic cells with a transposase from oryzias22 Sep 2026US 12,742,171 B2Dna Twopointo Inc.
- Methods for manufacturing genetically engineered CAR-T cells22 Sep 2026US 12,742,184 B2Crispr Therapeutics AG
- Methods and systems for barcode-assisted image registration and alignment25 Aug 2026US 12,718,906 B210x Genomics, Inc.
- SGRNA guiding PD1 gene for cleavage to achieve efficient integration of exogenous sequences11 Aug 2026US 12,703,861 B2BRL Medicine (Shanghai) Co., Ltd.
- Analytical device for real time luminescence during temperature hold and ramp as used in real time cellular thermal shift assay1 Oct 2026US 2026/0297593 A1The United States of America, as represented by the Secretary, Department of Health and Human Serv
- Biosynthesis of beta-lactam antibiotics24 Sep 2026US 2026/0286334 A1
- Targeted lnp compositions for in vivo immune cell engineering and methods of use thereof17 Sep 2026US 2026/0274918 A1CREATE Medicines, Inc.
- Use of chimera in targeted protein degradation technology17 Sep 2026US 2026/0274986 A1Sun Yat-Sen University
- Preferentially expressed antigen in melanoma (prame) t cell receptors and methods of use thereof10 Sep 2026US 2026/0263558 A1Regeneron Pharmaceuticals, Inc.
Most cited
By later US patents
- Methods and compositions for secretion of heterologous polypeptides327US 5,840,523 AGenetech, Inc. · 1998
- Expression and export technology of proteins as immunofusins276US 5,541,087 AFuji ImmunoPharmaceuticals Corporation · 1996
- Novel atrial natriuretic/vasodilator polypeptides181US 4,764,504 ABiotechnology Research Associates, J.V. · 1988
- Mature protein synthesis170US 4,338,397 APresident and Fellows of Harvard College · 1982
- Interleukin-1 receptors165US 4,968,607 AImmunex Corporation · 1990