Interleukin-1 receptors
AssigneeImmunex Corporation
InventorsSteven K. Dower, Carl J. March, John E. Sims, David L. Urdal
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Abstract
Mammalian Interleukin-1 receptor proteins (IL-1Rs), DNAs and expression vectors encoding mammalian IL-1Rs, and processes for producing mammalian IL-1Rs as products of cell culture, including recombinant systems, are disclosed.
Claims21
An isolated DNA sequence encoding a mammalian IL-1 receptor (IL-1R protein, or soluble truncated IL-1R protein which exhibits IL-1-binding activity.
A process for preparing a murine IL-1R, comprising culturing a suitable host cell comprising a vector according to claim 14 under conditions promoting expression.
A process for preparing a human IL-1R, comprising culturing a suitable host cell comprising a vector according to claim 17 under conditions promoting expression.
The clone GEMBL78(ATCC67563).
Dependencies are inferred from the claim text.