C12N 15/117
Nucleic acids having immunomodulatory properties
Official title: Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
C12N15/117 (Nucleic acids having immunomodulatory properties) appears on 520 US grants and 934 published applications in this corpus.
Search patents in C12N- Granted patents
- 520
- Published applications
- 934
- Assignees
- 362
- Inventors
- 1,171
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 0 | 0 |
| 1996 | 2 | 0 |
| 1997 | 1 | 0 |
| 1998 | 1 | 0 |
| 1999 | 2 | 0 |
| 2000 | 0 | 0 |
| 2001 | 4 | 1 |
| 2002 | 2 | 9 |
| 2003 | 4 | 27 |
| 2004 | 3 | 33 |
| 2005 | 2 | 38 |
| 2006 | 8 | 32 |
| 2007 | 8 | 21 |
| 2008 | 6 | 31 |
| 2009 | 15 | 31 |
| 2010 | 20 | 37 |
| 2011 | 30 | 44 |
| 2012 | 29 | 36 |
| 2013 | 31 | 42 |
| 2014 | 30 | 43 |
| 2015 | 31 | 35 |
| 2016 | 35 | 46 |
| 2017 | 19 | 41 |
| 2018 | 32 | 51 |
| 2019 | 42 | 45 |
| 2020 | 26 | 38 |
| 2021 | 18 | 47 |
| 2022 | 28 | 49 |
| 2023 | 26 | 52 |
| 2024 | 22 | 46 |
| 2025 | 26 | 37 |
| 2026 | 14 | 22 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Preventing and treating amyloid-beta deposition by stimulation of innate immunity6 Oct 2026US 12,751,964 B2New York University
- Immune inducer containing polynucleotide-peptide conjugate and pharmaceutical composition containing same21 Jul 2026US 12,685,780 B2Daiichi Sankyo Company, Limited
- TLR9 agonists21 Jul 2026US 12,686,870 B2SBI Biotech Co., Ltd.
- RNA preparations comprising purified modified RNA for reprogramming cells16 Jun 2026US 12,655,395 B2
- Compositions and methods for inducing an enhanced immune response using poxvirus vectors2 Jun 2026US 12,644,125 B2Bavarian Nordic A/S
- Rna preparations comprising purified modified rna for reprogramming cells1 Oct 2026US 2026/0297538 A1The Trustees of the University of Pennsylvania
- Immune inducer containing polynucleotide-peptide conjugate and pharmaceutical composition containing same24 Sep 2026US 2026/0284210 A1Daiichi Sankyo Company, Limited
- Short interspersed nuclear repeat element rna of imprinted micro-rna clusters mediate intrinsic type iii interferon-driven viral resistance20 Aug 2026US 2026/0240890 A1University of South Florida
- Methods of eliciting an immune response against clostridium perfringens and/or necrotic enteritis and compositions for use thereof13 Aug 2026US 2026/0232784 A1University of Saskatchewan
- Immune-enhancing rnas for combination with chimeric antigen receptor therapy30 Jul 2026US 2026/0216224 A1Novartis AG
Most cited
By later US patents
- Immunostimulatory nucleic acid molecules472US 6,207,646 B1Coley Pharmaceutical Group, Inc. · 2001
- Immunostimulatory nucleic acid molecules461US 6,239,116 B1Coley Pharmaceutical Group, Inc. · 2001
- RNA containing modified nucleosides and methods of use thereof353US 8,278,036 B2The Trustees of the University of Pennsylvania · 2012
- Immunomodulatory oligonucleotides335US 6,194,388 B1Coley Pharmaceutical Group, Inc. · 2001
- Immune stimulation by phosphorothioate oligonucleotide analogs238US 5,663,153 AIsis Pharmaceuticals, Inc. · 1997