C12M 45/02
Means for pre-treatment of biological substances: by mechanical forces
Official title: {by mechanical forces; Stirring; Trituration; Comminuting (crushing, pulverizing, disintegrating in general B02C)}
C12M45/02 (Means for pre-treatment of biological substances: by mechanical forces) appears on 431 US grants and 626 published applications in this corpus.
Search patents in C12M- Granted patents
- 431
- Published applications
- 626
- Assignees
- 362
- Inventors
- 1,243
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 1 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 3 | 0 |
| 1983 | 2 | 0 |
| 1984 | 2 | 0 |
| 1985 | 2 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 2 | 0 |
| 1991 | 1 | 0 |
| 1992 | 2 | 0 |
| 1993 | 2 | 0 |
| 1994 | 2 | 0 |
| 1995 | 6 | 0 |
| 1996 | 4 | 0 |
| 1997 | 0 | 0 |
| 1998 | 5 | 0 |
| 1999 | 1 | 0 |
| 2000 | 2 | 0 |
| 2001 | 2 | 0 |
| 2002 | 1 | 3 |
| 2003 | 2 | 6 |
| 2004 | 3 | 9 |
| 2005 | 2 | 9 |
| 2006 | 4 | 5 |
| 2007 | 2 | 14 |
| 2008 | 3 | 16 |
| 2009 | 2 | 15 |
| 2010 | 7 | 30 |
| 2011 | 10 | 24 |
| 2012 | 15 | 28 |
| 2013 | 19 | 34 |
| 2014 | 24 | 17 |
| 2015 | 30 | 31 |
| 2016 | 14 | 38 |
| 2017 | 16 | 34 |
| 2018 | 20 | 28 |
| 2019 | 29 | 39 |
| 2020 | 33 | 38 |
| 2021 | 22 | 49 |
| 2022 | 32 | 29 |
| 2023 | 19 | 42 |
| 2024 | 28 | 43 |
| 2025 | 30 | 32 |
| 2026 | 19 | 13 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Device, a method and a system for dispersing cell clumps6 Oct 2026US 12,753,378 B2Suzhou Etta Biotech Co., Ltd.
- Method and apparatus for processing tissue samples29 Sep 2026US 12,747,422 B2S2 Genomics, Inc.
- Method for mechanically separating tissue and cells constituting biological tissue15 Sep 2026US 12,735,671 B2
- Systems and methods for tissue processing and preparation of cell suspension therefrom15 Sep 2026US RE51,030 E1AVITA Medical Americas, LLC
- Thyroid manufacturing process and specifications21 Jul 2026US 12,686,850 B2Bioiberica, S.A.U.
- Atraumatically formed tissue compositions, devices and methods of preparation and treatment17 Sep 2026US 2026/0272503 A1TissueMill Technologies LLC
- Processes for converting biomass into high-value products10 Sep 2026US 2026/0265674 A1The Texas A&M University System
- Process and equipment for effecting lysis of cells13 Aug 2026US 2026/0234538 A1Whole Green Foods Pty Ltd
- Dual gate outfeed for hydrolyzer30 Jul 2026US 2026/0216766 A1Bouldin Corporation
- Cartridge for processing biological samples and devices and methods thereof23 Jul 2026US 2026/0210818 A1Cellsonics Inc.
Most cited
By later US patents
- Processing biomass176US 7,932,065 B2Xyleco, Inc. · 2011
- Tissue dissociating system and method167US 5,786,207 AUniversity of Pittsburgh · 1998
- Anaerobic digester system158US 6,299,774 B12001
- Methods for harvesting adipose tissue containing autologous microvascular endothelial cells127US 5,744,360 ABaxter International Inc. · 1998
- Continuous counter-current organosolv processing of lignocellulosic feedstocks95US 7,465,791 B1Lignol Innovations Ltd. · 2008