C12M 27/12
Roller bottles
Official title: {Roller bottles; Roller tubes}
C12M27/12 (Roller bottles) appears on 67 US grants and 57 published applications in this corpus.
Search patents in C12M- Granted patents
- 67
- Published applications
- 57
- Assignees
- 53
- Inventors
- 152
- Latest grant
- 19 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 1 | 0 |
| 1977 | 0 | 0 |
| 1978 | 0 | 0 |
| 1979 | 0 | 0 |
| 1980 | 1 | 0 |
| 1981 | 1 | 0 |
| 1982 | 2 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 2 | 0 |
| 1989 | 3 | 0 |
| 1990 | 4 | 0 |
| 1991 | 2 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 2 | 0 |
| 1995 | 2 | 0 |
| 1996 | 4 | 0 |
| 1997 | 5 | 0 |
| 1998 | 1 | 0 |
| 1999 | 2 | 0 |
| 2000 | 3 | 0 |
| 2001 | 0 | 0 |
| 2002 | 1 | 4 |
| 2003 | 2 | 0 |
| 2004 | 2 | 5 |
| 2005 | 1 | 1 |
| 2006 | 2 | 4 |
| 2007 | 1 | 1 |
| 2008 | 1 | 3 |
| 2009 | 0 | 1 |
| 2010 | 2 | 2 |
| 2011 | 0 | 2 |
| 2012 | 1 | 3 |
| 2013 | 1 | 1 |
| 2014 | 2 | 2 |
| 2015 | 1 | 3 |
| 2016 | 2 | 0 |
| 2017 | 0 | 0 |
| 2018 | 1 | 1 |
| 2019 | 2 | 2 |
| 2020 | 2 | 1 |
| 2021 | 1 | 2 |
| 2022 | 1 | 4 |
| 2023 | 1 | 7 |
| 2024 | 2 | 3 |
| 2025 | 2 | 2 |
| 2026 | 1 | 3 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Apparatus, methods, and systems for maintaining healthy plankton populations19 May 2026US 12,630,797 B2Industrial Plankton Inc.
- Scalable primate pluripotent stem cell aggregate suspension culture25 Feb 2025US 12,234,477 B2ViaCyte, Inc.
- Drawer system for cultivating tissue14 Jan 2025US 12,195,711 B1Humacyte, Inc.
- Cell culture bottle26 Nov 2024US 12,152,226 B2Green Elephant Biotech GmbH
- Continuous automated perfusion culture analysis system (CAPCAS) and applications of same26 Mar 2024US 11,939,563 B2Vanderbilt University
- Apparatus, methods, and systems for maintaining healthy plankton populations10 Sep 2026US 2026/0265662 A1Industiral Plankton Inc.
- System and Method for Production of Advanced Therapy Manufactured Products (ATMPs)27 Aug 2026US 2026/0250616 A1Sedna Cell Care, Corp.
- A rotating tissue culture insert for the position inside a rotatable roller bottle partially filled with a liquid for the cultivation of cells16 Jul 2026US 2026/0201304 A1UniversitäT ZüRich
- Multi-layer cell culture container26 Jun 2025US 2025/0207075 A1
- Systems, devices, and methods for fluid control in a cell processing system24 Apr 2025US 2025/0129321 A1
Most cited
By later US patents
- High density cell culture system85US 5,330,908 AThe United States of America as represented by the Administrator of the National Aeronautics and Space Administration · 1994
- Roller bottle75US 5,866,419 A1999
- Controlled hydrodynamic cell culture environment for three dimensional tissue growth74US 6,001,643 AC-Med Inc. · 1999
- Cell culture vessel50US 6,150,159 ACellon S.A. · 2000
- Plastic roller bottle for suspension cultures49US 4,717,668 ABaxter Travenol Laboratories, Inc. · 1988