C07D 499/88
Compounds with a double bond between positions 2 and 3 and a
Official title: Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
C07D499/88 (Compounds with a double bond between positions 2 and 3 and a) appears on 221 US grants and 27 published applications in this corpus.
Search patents in C07D- Granted patents
- 221
- Published applications
- 27
- Assignees
- 51
- Inventors
- 268
- Latest grant
- 12 May 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1977 | 1 | 0 |
| 1978 | 2 | 0 |
| 1979 | 2 | 0 |
| 1980 | 4 | 0 |
| 1981 | 8 | 0 |
| 1982 | 4 | 0 |
| 1983 | 9 | 0 |
| 1984 | 15 | 0 |
| 1985 | 17 | 0 |
| 1986 | 17 | 0 |
| 1987 | 17 | 0 |
| 1988 | 19 | 0 |
| 1989 | 12 | 0 |
| 1990 | 15 | 0 |
| 1991 | 7 | 0 |
| 1992 | 7 | 0 |
| 1993 | 6 | 0 |
| 1994 | 7 | 0 |
| 1995 | 3 | 0 |
| 1996 | 8 | 0 |
| 1997 | 10 | 0 |
| 1998 | 7 | 0 |
| 1999 | 2 | 0 |
| 2000 | 3 | 0 |
| 2001 | 1 | 0 |
| 2002 | 1 | 2 |
| 2003 | 1 | 0 |
| 2004 | 0 | 6 |
| 2005 | 0 | 1 |
| 2006 | 2 | 2 |
| 2007 | 0 | 0 |
| 2008 | 1 | 3 |
| 2009 | 0 | 3 |
| 2010 | 3 | 0 |
| 2011 | 1 | 0 |
| 2012 | 0 | 0 |
| 2013 | 0 | 1 |
| 2014 | 0 | 1 |
| 2015 | 1 | 1 |
| 2016 | 1 | 0 |
| 2017 | 0 | 0 |
| 2018 | 0 | 0 |
| 2019 | 1 | 1 |
| 2020 | 1 | 1 |
| 2021 | 1 | 1 |
| 2022 | 0 | 2 |
| 2023 | 1 | 0 |
| 2024 | 0 | 0 |
| 2025 | 2 | 2 |
| 2026 | 1 | 0 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- C07D 499/883With a substituted hydrocarbon radical attached in position 34
- C07D 499/887With a hetero atom or a carbon atom having three bonds to4
- C07D 499/893With a hetero ring or a condensed hetero ring system, directly attached3
- C07D 499/881With a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position1
Recent patents
- Beta-lactam compounds and methods of use thereof12 May 2026US 12,624,382 B2The University of Hong Kong
- Fluorescence quenching immunoassay1 Jul 2025US 12,345,641 B2IDEZZ Laboratories, Inc.
- β-lactam-cannabinoid conjugate molecules25 Mar 2025US 12,257,307 B2Diverse Biotech, Inc.
- Antibacterial compounds, pharmaceutical compositions, and methods of treating bacterial infections26 Sep 2023US 11,767,329 B1Miralogx LLC
- Antibacterial agents against D,D- and L,D-transpeptidases10 Aug 2021US 11,084,833 B2The Johns Hopkins University
- Penem antibacterials against mycobacterial pathogens and d,d- and l,d transpeptidases11 Sep 2025US 2025/0282796 A1The Johns Hopkins University
- Beta-Lactam-Cannabinoid Conjugate Molecules10 Jul 2025US 2025/0222118 A1Diverse Biotech, Inc.
- Beta-Lactam-Cannabinoid Conjugate Molecules18 Aug 2022US 2022/0257778 A1Diverse Biotech, Inc.
- Fluorescence quenching immunoassay17 Mar 2022US 2022/0082501 A1IDEXX Laboratories, Inc.
- Beta-lactam compounds and methods of use thereof8 Jul 2021US 2021/0207188 A1The University of Hong Kong
Most cited
By later US patents
- .beta.-Lactam antibacterial agents, their use in pharmaceutical compositions, and intermediates136US 4,282,236 ABeecham Group Limited · 1981
- 2-alkylthiopenem derivatives45US 4,619,924 APfizer Inc. · 1986
- 6-(1'-Hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid37US 4,260,618 AMerck & Co., Inc. · 1981
- Antibacterial agents, and 4-thio azetidinone intermediates32US 4,272,437 ABristol-Myers Company · 1981
- Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group32US 4,479,947 AMerck & Co., Inc. · 1984