C07D 239/557
With carbon atoms having three bonds to hetero atoms with at the
Official title: with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
C07D239/557 (With carbon atoms having three bonds to hetero atoms with at the) appears on 106 US grants and 107 published applications in this corpus.
Search patents in C07D- Granted patents
- 106
- Published applications
- 107
- Assignees
- 99
- Inventors
- 470
- Latest grant
- 27 Jan 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 4 | 0 |
| 1977 | 2 | 0 |
| 1978 | 2 | 0 |
| 1979 | 0 | 0 |
| 1980 | 2 | 0 |
| 1981 | 3 | 0 |
| 1982 | 3 | 0 |
| 1983 | 2 | 0 |
| 1984 | 2 | 0 |
| 1985 | 1 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 2 | 0 |
| 1989 | 3 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 2 | 0 |
| 1993 | 0 | 0 |
| 1994 | 1 | 0 |
| 1995 | 0 | 0 |
| 1996 | 0 | 0 |
| 1997 | 0 | 0 |
| 1998 | 0 | 0 |
| 1999 | 1 | 0 |
| 2000 | 4 | 0 |
| 2001 | 2 | 0 |
| 2002 | 1 | 4 |
| 2003 | 3 | 3 |
| 2004 | 2 | 7 |
| 2005 | 3 | 5 |
| 2006 | 2 | 3 |
| 2007 | 3 | 5 |
| 2008 | 2 | 4 |
| 2009 | 1 | 1 |
| 2010 | 3 | 5 |
| 2011 | 1 | 3 |
| 2012 | 1 | 4 |
| 2013 | 3 | 6 |
| 2014 | 3 | 3 |
| 2015 | 5 | 6 |
| 2016 | 3 | 6 |
| 2017 | 5 | 7 |
| 2018 | 4 | 5 |
| 2019 | 6 | 7 |
| 2020 | 6 | 3 |
| 2021 | 0 | 1 |
| 2022 | 5 | 4 |
| 2023 | 0 | 3 |
| 2024 | 2 | 3 |
| 2025 | 1 | 6 |
| 2026 | 1 | 3 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Triaryl compounds for treatment of PD-L1 diseases27 Jan 2026US 12,533,354 B2ChemoCentryx, Inc.
- Crystalline forms of tenofovir alafenamide21 Jan 2025US 12,202,849 B2Gilead Sciences, Inc.
- Nicotine salts, co-crystals, and salt co-crystal complexes31 Dec 2024US 12,180,179 B2R. J. Reynolds Tobacco Company
- 3-((R)-2-(amino-2-phenylethyl)-1-(2-fluoro-6 trifluoromethyl benzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione or a salt thereof, process for its preparation, and its use in the synthesis of elagolix2 Jan 2024US 11,858,901 B2Moehs Iberica, S.L.
- Method for producing orotic acid derivative27 Sep 2022US 11,453,648 B2Showa Denko K. K.
- Crystalline forms of tenofovir alafenamide6 Aug 2026US 2026/0226087 A1Gilead Sciences, Inc.
- Gpr35 modulators30 Jul 2026US 2026/0216198 A1ThirtyFiveBio Limited
- Crystalline salt forms of n-((1-(2-(tert-butylamino)-2-oxoethyl)piperidin-4-yl) methyl)-3-chloro-5-fluorobenzamide and methods of use thereof2 Apr 2026US 2026/0092037 A1Praxis Precision Medicines, Inc.
- Crystalline forms of tenofovir alafenamide3 Jul 2025US 2025/0215031 A1Gilead Sciences, Inc.
- Heterocyclic compound, preparation method therefor, and use thereof12 Jun 2025US 2025/0188042 A1Sichuan University
Most cited
By later US patents
- 2,4,5,6-Tetrasubstituted pyrimidines and salts thereof46US 3,975,384 ABoehringer Ingelheim GmbH · 1976
- N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase42US 7,169,780 B2Istitute Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. · 2007
- Modulators of protein tyrosine phosphatases (PTPASES)40US 6,262,044 B1Novo Nordisk A/S · 2001
- 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts38US 4,746,352 AHoffmann-La Roche Inc. · 1988
- Novel pyrimidopyrimidine derivative, process for producing it and pharmaceutical composition35US 4,886,807 ANippon Zoki Pharmaceutical Co., Ltd. · 1989