C07D 239/28
With hetero atoms or with carbon atoms having three bonds to hetero
Official title: with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
C07D239/28 (With hetero atoms or with carbon atoms having three bonds to hetero) appears on 7,193 US grants and 6,168 published applications in this corpus.
Search patents in C07D- Granted patents
- 7,193
- Published applications
- 6,168
- Assignees
- 2,301
- Inventors
- 18,474
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 77 | 0 |
| 1977 | 57 | 0 |
| 1978 | 70 | 0 |
| 1979 | 53 | 0 |
| 1980 | 74 | 0 |
| 1981 | 84 | 0 |
| 1982 | 63 | 0 |
| 1983 | 68 | 0 |
| 1984 | 84 | 0 |
| 1985 | 102 | 0 |
| 1986 | 107 | 0 |
| 1987 | 101 | 0 |
| 1988 | 94 | 0 |
| 1989 | 109 | 0 |
| 1990 | 123 | 0 |
| 1991 | 118 | 0 |
| 1992 | 127 | 0 |
| 1993 | 132 | 0 |
| 1994 | 141 | 0 |
| 1995 | 135 | 0 |
| 1996 | 131 | 0 |
| 1997 | 144 | 0 |
| 1998 | 147 | 0 |
| 1999 | 134 | 0 |
| 2000 | 125 | 0 |
| 2001 | 149 | 26 |
| 2002 | 162 | 146 |
| 2003 | 149 | 236 |
| 2004 | 138 | 274 |
| 2005 | 116 | 282 |
| 2006 | 164 | 246 |
| 2007 | 141 | 244 |
| 2008 | 131 | 258 |
| 2009 | 166 | 294 |
| 2010 | 195 | 310 |
| 2011 | 179 | 282 |
| 2012 | 228 | 271 |
| 2013 | 266 | 284 |
| 2014 | 273 | 306 |
| 2015 | 283 | 337 |
| 2016 | 242 | 283 |
| 2017 | 278 | 302 |
| 2018 | 230 | 235 |
| 2019 | 199 | 212 |
| 2020 | 189 | 237 |
| 2021 | 135 | 221 |
| 2022 | 156 | 209 |
| 2023 | 119 | 224 |
| 2024 | 115 | 197 |
| 2025 | 108 | 134 |
| 2026 | 82 | 118 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Crystalline forms of a BTK inhibitor6 Oct 2026US 12,751,949 B2Novartis AG
- Diaminopyrimidine carboxamide inhibitors of HPK16 Oct 2026US 12,753,163 B2Merck Sharp & Dohme Corp.
- P38alpha mitogen-activated protein kinase inhibitors6 Oct 2026US 12,753,184 B2Gen1E Lifesciences Inc.
- Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents22 Sep 2026US 12,740,943 B2ModernaTX, Inc.
- PIKfyve kinase inhibitors22 Sep 2026US 12,741,960 B2Acurastem Incorporated
- Probenecid compounds for the treatment of inflammasome-mediated lung disease8 Oct 2026US 2026/0308131 A1Bacainn Biotherapeutics, Ltd.
- Neuroactive androgen receptor modulators and use thereof1 Oct 2026US 2026/0294908 A1ENDOCHEM PHARMACEUTICALS (BEIJING) CO., LTD. Beijing
- Inhibitors of spinster homolog 2 (spns2) for use in therapy1 Oct 2026US 2026/0297044 A1University of Virginia Patent Foundation
- Modulators of sortilin activity24 Sep 2026US 2026/0285802 A1
- Hiv-1p rotease inhibitors and uses thereof17 Sep 2026US 2026/0272926 A1Purdue Research Foundation
Most cited
By later US patents
- Pyrimidine, cyanoguanidines as K-channel blockers1,019US 5,633,374 AThe Upjohn Company · 1997
- Pyrimidine derivatives for labeled binding partners639US 5,502,177 AGilead Sciences, Inc. · 1996
- Pyrimidine derivatives488US 6,005,096 AGilead Sciences, Inc. · 1999
- Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates468US 5,700,920 ANovartis AG · 1997
- Pyrimidine derivatives for labeled binding partners456US 5,763,588 AGilead Sciences, Inc. · 1998