Hiv-1p rotease inhibitors and uses thereof
AssigneePurdue Research Foundation
InventorsArun K. Ghosh, Hiroaki Mitsuya
Life of this patent
Estimating the term…
Abstract
Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein A is aryl; B is heterocyclyl; Q is alkyl or heterocyclyl; R2 is alkyl; R3 is aryl, benzthiazole, benzoxazole, benzofuranyl or indolyl; each R4 is, independently, alkyl, alkoxy, aryl, heterocyclyl, halo, hydroxy or amino; and n is an integer from 0 to 3; methods for treating an HIV infection or AIDS comprising administering a therapeutically effective amount of one or more compounds of formula (I) to a subject in need thereof.
Claims32
A compound of the formula (I):
- or a pharmaceutically acceptable salt thereof, wherein:
- A is aryl;
- B is heterocyclyl;
- Q is alkyl or heterocyclyl;
- R2 is alkyl;
- R3 is aryl, benzthiazole, benzoxazole, benzofuranyl or indolyl;
- each R4 is, independently, alkyl, alkoxy, aryl, heterocyclyl, halo, hydroxy or amino;
- and
- n is an integer from 0 to 3.
-5. (canceled)
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-57. (canceled)
Dependencies are inferred from the claim text.