C07D 239/49
With an aralkyl radical, or substituted aralkyl radical, attached in position 5
Official title: with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
C07D239/49 (With an aralkyl radical, or substituted aralkyl radical, attached in position 5) appears on 143 US grants and 126 published applications in this corpus.
Search patents in C07D- Granted patents
- 143
- Published applications
- 126
- Assignees
- 82
- Inventors
- 430
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 8 | 0 |
| 1977 | 5 | 0 |
| 1978 | 6 | 0 |
| 1979 | 6 | 0 |
| 1980 | 5 | 0 |
| 1981 | 6 | 0 |
| 1982 | 2 | 0 |
| 1983 | 2 | 0 |
| 1984 | 2 | 0 |
| 1985 | 1 | 0 |
| 1986 | 5 | 0 |
| 1987 | 1 | 0 |
| 1988 | 3 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 1 | 0 |
| 1996 | 1 | 0 |
| 1997 | 2 | 0 |
| 1998 | 2 | 0 |
| 1999 | 0 | 0 |
| 2000 | 0 | 0 |
| 2001 | 2 | 2 |
| 2002 | 3 | 0 |
| 2003 | 2 | 2 |
| 2004 | 2 | 5 |
| 2005 | 4 | 8 |
| 2006 | 1 | 4 |
| 2007 | 1 | 2 |
| 2008 | 3 | 1 |
| 2009 | 1 | 1 |
| 2010 | 4 | 4 |
| 2011 | 3 | 7 |
| 2012 | 2 | 3 |
| 2013 | 4 | 6 |
| 2014 | 5 | 4 |
| 2015 | 1 | 9 |
| 2016 | 6 | 6 |
| 2017 | 7 | 8 |
| 2018 | 7 | 9 |
| 2019 | 3 | 15 |
| 2020 | 9 | 3 |
| 2021 | 4 | 9 |
| 2022 | 2 | 6 |
| 2023 | 2 | 3 |
| 2024 | 2 | 3 |
| 2025 | 3 | 4 |
| 2026 | 1 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Diaminopyrimidine carboxamide inhibitors of HPK16 Oct 2026US 12,753,163 B2Merck Sharp & Dohme Corp.
- Substituted pyrimidines as vaccine adjuvants14 Oct 2025US 12,440,560 B2Sumitomo Pharma Co., Ltd.
- Water soluble adjuvant and composition containing same30 Sep 2025US 12,427,192 B2Sumitomo Pharma Co., Ltd.
- Methods and compositions for optochemical control of CRISPR-CAS923 Sep 2025US 12,421,507 B2The Brigham and Womens's Hospital, Inc.
- Carboxylic acid compounds3 Sep 2024US 12,077,510 B2Sumitomo Pharma Co., Ltd.
- New compounds and treatment of renal cell carcinoma27 Aug 2026US 2026/0248788 A1Trustlife Therapeutics Inc.
- Pyrimidine compound26 Feb 2026US 2026/0053911 A1Sumitomo Pharma Co., Ltd.
- Prep binding ligands18 Sep 2025US 2025/0288559 A1Polku Therapeutics Oy
- Photoredox methods for radiocyanation of arenes and use thereof24 Apr 2025US 2025/0129016 A1The University of North Carolina at Chapel Hill
- Pyrimidine compounds containing acidic groups6 Mar 2025US 2025/0073236 A1Apros Therapeutics, Inc.
Most cited
By later US patents
- 2,4-diamino pyrimidine compounds having anti-cell proliferative activity192US 6,593,326 B1AstraZeneca AB · 2003
- HIV inhibiting pyrimidine derivative110US 6,197,779 B1Janssen Pharmaceutica NV · 2001
- Integrin antagonists57US 6,489,333 B2Bristol-Meyers Squibb Pharma Company · 2002
- Compositions and methods for inhibition of the JAK pathway55US 7,834,024 B2Rigel Pharmaceuticals, Inc. · 2010
- HIV Inhibiting pyrimidine derivatives50US 6,440,986 B2Janssen Pharmaceutica NV · 2002