C07D 239/48
Two nitrogen atoms
C07D239/48 (Two nitrogen atoms) appears on 1,342 US grants and 1,374 published applications in this corpus.
Search patents in C07D- Granted patents
- 1,342
- Published applications
- 1,374
- Assignees
- 581
- Inventors
- 4,087
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 20 | 0 |
| 1977 | 9 | 0 |
| 1978 | 12 | 0 |
| 1979 | 12 | 0 |
| 1980 | 18 | 0 |
| 1981 | 24 | 0 |
| 1982 | 14 | 0 |
| 1983 | 9 | 0 |
| 1984 | 13 | 0 |
| 1985 | 17 | 0 |
| 1986 | 19 | 0 |
| 1987 | 12 | 0 |
| 1988 | 15 | 0 |
| 1989 | 13 | 0 |
| 1990 | 19 | 0 |
| 1991 | 12 | 0 |
| 1992 | 8 | 0 |
| 1993 | 10 | 0 |
| 1994 | 11 | 0 |
| 1995 | 11 | 0 |
| 1996 | 10 | 0 |
| 1997 | 22 | 0 |
| 1998 | 14 | 0 |
| 1999 | 16 | 0 |
| 2000 | 9 | 0 |
| 2001 | 13 | 7 |
| 2002 | 17 | 15 |
| 2003 | 22 | 43 |
| 2004 | 25 | 42 |
| 2005 | 23 | 64 |
| 2006 | 23 | 63 |
| 2007 | 25 | 65 |
| 2008 | 31 | 58 |
| 2009 | 44 | 65 |
| 2010 | 46 | 77 |
| 2011 | 57 | 85 |
| 2012 | 51 | 58 |
| 2013 | 68 | 74 |
| 2014 | 59 | 71 |
| 2015 | 58 | 68 |
| 2016 | 47 | 66 |
| 2017 | 72 | 81 |
| 2018 | 48 | 56 |
| 2019 | 61 | 64 |
| 2020 | 71 | 50 |
| 2021 | 33 | 46 |
| 2022 | 33 | 41 |
| 2023 | 21 | 44 |
| 2024 | 14 | 32 |
| 2025 | 16 | 23 |
| 2026 | 15 | 16 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Diaminopyrimidine carboxamide inhibitors of HPK16 Oct 2026US 12,753,163 B2Merck Sharp & Dohme Corp.
- PIKfyve kinase inhibitors22 Sep 2026US 12,741,960 B2Acurastem Incorporated
- Preparation method for pyrimidine-2-amine8 Sep 2026US 12,729,185 B2Institute for Basic Science
- Cyano-pyrimidine inhibitors of EGFR/HER24 Aug 2026US 12,698,261 B2Dana-Farber Cancer Institute, Inc.
- Heteroaryl compounds and therapeutic uses thereof in conditions associated with the alteration of the activity of beta-glucocerebrosidase23 Jun 2026US 12,661,342 B2Gt Gain Therapeutics SA
- Modulators of sortilin activity24 Sep 2026US 2026/0285802 A1
- Ulk1 inhibitor, preparation method therefor and use thereof17 Sep 2026US 2026/0274819 A1Dovetree Medicines Unus, Inc.
- Thymidylate synthase inhibitors and uses thereof3 Sep 2026US 2026/0258000 A1University of Florida Research Foundation, Inc.
- Compounds, compositions and methods of use to treat hypoparathyroidism and osteoporosis3 Sep 2026US 2026/0258007 A1Septerna, Inc.
- Ras inhibitors and methods of using the same3 Sep 2026US 2026/0258018 A1
Most cited
By later US patents
- Pyrimidine, cyanoguanidines as K-channel blockers1,019US 5,633,374 AThe Upjohn Company · 1997
- Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates468US 5,700,920 ANovartis AG · 1997
- Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates409US 5,610,300 ACiba-Geigy Corporation · 1997
- Substituted 2-anilinopyrimidines useful as protein kinase inhibitors201US 5,958,935 ACelltech Therapeutics Limited · 1999
- Bi-aryl meta-pyrimidine inhibitors of kinases194US 7,528,143 B2TargeGen, Inc. · 2009