C07C 405/0008
Analogues having the carboxyl group in the side-chains replaced by other functional
Official title: {Analogues having the carboxyl group in the side-chains replaced by other functional groups}
C07C405/0008 (Analogues having the carboxyl group in the side-chains replaced by other functional) appears on 959 US grants and 94 published applications in this corpus.
Search patents in C07C- Granted patents
- 959
- Published applications
- 94
- Assignees
- 100
- Inventors
- 488
- Latest grant
- 18 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 39 | 0 |
| 1977 | 47 | 0 |
| 1978 | 186 | 0 |
| 1979 | 73 | 0 |
| 1980 | 81 | 0 |
| 1981 | 239 | 0 |
| 1982 | 36 | 0 |
| 1983 | 14 | 0 |
| 1984 | 25 | 0 |
| 1985 | 13 | 0 |
| 1986 | 10 | 0 |
| 1987 | 11 | 0 |
| 1988 | 13 | 0 |
| 1989 | 11 | 0 |
| 1990 | 6 | 0 |
| 1991 | 5 | 0 |
| 1992 | 8 | 0 |
| 1993 | 2 | 0 |
| 1994 | 7 | 0 |
| 1995 | 4 | 0 |
| 1996 | 8 | 0 |
| 1997 | 8 | 0 |
| 1998 | 7 | 0 |
| 1999 | 8 | 0 |
| 2000 | 4 | 0 |
| 2001 | 8 | 1 |
| 2002 | 14 | 6 |
| 2003 | 5 | 4 |
| 2004 | 5 | 3 |
| 2005 | 2 | 8 |
| 2006 | 6 | 7 |
| 2007 | 3 | 2 |
| 2008 | 1 | 5 |
| 2009 | 2 | 5 |
| 2010 | 2 | 6 |
| 2011 | 5 | 5 |
| 2012 | 3 | 3 |
| 2013 | 5 | 3 |
| 2014 | 5 | 3 |
| 2015 | 2 | 7 |
| 2016 | 5 | 4 |
| 2017 | 3 | 3 |
| 2018 | 4 | 3 |
| 2019 | 3 | 2 |
| 2020 | 2 | 2 |
| 2021 | 1 | 5 |
| 2022 | 3 | 3 |
| 2023 | 1 | 1 |
| 2024 | 3 | 2 |
| 2025 | 0 | 1 |
| 2026 | 1 | 0 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Process for the preparation of a nitric oxide donating prostaglandin analogue18 Aug 2026US 12,709,597 B2Nicox S A.
- Co-crystals of NURR1-lbd in complex with a cyclopentenone prostaglandin and modulators of NURR116 Jul 2024US 12,036,195 B2Nanyang Technological University
- Prostaglandin F2 alpha derivatives for decreasing intraocular pressure18 Jun 2024US 12,012,375 B2Gurus Biopharm Limited Liability Company
- Total synthesis of prostaglandin J natural products by stereoretentive metathesis9 Jan 2024US 11,866,398 B2California Institute of Technology
- High penetration prodrug compositions of prostaglandins and related compounds17 Jan 2023US 11,555,014 B2Techfields Pharma Co., Ltd.
- Industrial process for the preparation of hexanoic acid, 6-(nitrooxy)-, (1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester and high pure product16 Oct 2025US 2025/0320182 A1Nicox S A.
- Process for the preparation of a nitric oxide donating prostaglandin analogue16 May 2024US 2024/0158345 A1Nicox S A.
- Industrial process for the preparation of hexanoic acid, 6-(nitrooxy)-, (1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester and high pure product18 Jan 2024US 2024/0018096 A1Nicox S A.
- High penetration prodrug compositions of prostaglandins and related compounds8 Jun 2023US 2023/0174476 A1Techfields Pharma Co., Ltd.
- Co-crystals of nurr1-lbd in complex with a cyclopentenone prostaglandin and modulators of nurr120 Oct 2022US 2022/0331271 A1Nanyang Technological University
Most cited
By later US patents
- 3-Hydroxybutyric acid polymers114US 4,427,614 AImperial Chemical Industries PLC · 1984
- Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension102US 5,889,052 AAlcon Laboraties, Inc. · 1999
- Process for topically producing cutaneous vasodilation for the treatment of vasospastic or ischemic conditions75US 4,311,707 AAmerican Cyanamid Company · 1982
- Prostaglandin derivatives71US 4,812,457 AResearch Development Corporation · 1989
- Methano carbacyclin analogs62US 4,349,689 AThe Upjohn Company · 1982