Compounds containing a five-membered ring having two side-chains in ortho position to
Official title: Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins {; Analogues or derivatives thereof}
C07C405/00 (Compounds containing a five-membered ring having two side-chains in ortho position to) appears on 2,101 US grants and 291 published applications in this corpus.
Search patents in C07C- Granted patents
- 2,101
- Published applications
- 291
- Assignees
- 230
- Inventors
- 1,144
- Latest grant
- 18 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 207 | 0 |
| 1977 | 182 | 0 |
| 1978 | 304 | 0 |
| 1979 | 164 | 0 |
| 1980 | 157 | 0 |
| 1981 | 309 | 0 |
| 1982 | 82 | 0 |
| 1983 | 31 | 0 |
| 1984 | 45 | 0 |
| 1985 | 39 | 0 |
| 1986 | 21 | 0 |
| 1987 | 33 | 0 |
| 1988 | 29 | 0 |
| 1989 | 33 | 0 |
| 1990 | 17 | 0 |
| 1991 | 23 | 0 |
| 1992 | 32 | 0 |
| 1993 | 18 | 0 |
| 1994 | 19 | 0 |
| 1995 | 19 | 0 |
| 1996 | 15 | 0 |
| 1997 | 22 | 0 |
| 1998 | 14 | 0 |
| 1999 | 14 | 0 |
| 2000 | 13 | 0 |
| 2001 | 22 | 5 |
| 2002 | 26 | 12 |
| 2003 | 13 | 15 |
| 2004 | 8 | 9 |
| 2005 | 5 | 16 |
| 2006 | 8 | 15 |
| 2007 | 11 | 16 |
| 2008 | 9 | 16 |
| 2009 | 12 | 24 |
| 2010 | 9 | 21 |
| 2011 | 16 | 20 |
| 2012 | 13 | 15 |
| 2013 | 15 | 17 |
| 2014 | 16 | 14 |
| 2015 | 11 | 17 |
| 2016 | 13 | 7 |
| 2017 | 7 | 9 |
| 2018 | 7 | 6 |
| 2019 | 10 | 3 |
| 2020 | 7 | 6 |
| 2021 | 2 | 7 |
| 2022 | 5 | 5 |
| 2023 | 3 | 7 |
| 2024 | 5 | 5 |
| 2025 | 3 | 3 |
| 2026 | 3 | 1 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Recent patents
- Process for the preparation of a nitric oxide donating prostaglandin analogue18 Aug 2026US 12,709,597 B2Nicox S A.
- Key intermediate for synthesis of prostaglandin compound and preparation method thereof12 May 2026US 12,623,992 B2Shenzhen Catalys Technology Co., Ltd
- Processes and intermediates for the preparations of Carboprost and Carboprost Tromethamine, and Carboprost Tromethamine prepared therefrom3 Mar 2026US 12,565,468 B2Chirogate International Inc.
- Methods for synthesis of the tricyclic prostaglandin D2 metabolite methyl ester11 Nov 2025US 12,466,791 B2Purdue Research Foundation
- Processes and intermediates for the preparation of carbaprostacyclin analogues30 Sep 2025US 12,428,361 B2Chirogate International Inc.
- Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester5 Mar 2026US 2026/0062381 A1Purdue Research Foundation
- Industrial process for the preparation of hexanoic acid, 6-(nitrooxy)-, (1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester and high pure product16 Oct 2025US 2025/0320182 A1Nicox S A.
- Processes and intermediates for the preparation of carbaprostacyclin analogues2 Oct 2025US 2025/0304519 A1Chirogate International Inc.
- Treprostinil prodrugs15 May 2025US 2025/0154181 A1United Therapeutics Corporation
- Process for the preparation of a nitric oxide donating prostaglandin analogue16 May 2024US 2024/0158345 A1Nicox S A.
Most cited
- Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support822US 5,288,514 AThe Regents of the University of California · 1994
- Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents217US 5,688,819 AAllergan, Inc. · 1997
- Non-acidic cyclopentane heptanoic acid,2-cycloalkyl or arylalkyl derivatives as therapeutic agents177US 6,403,649 B1Allergan Sales, Inc. · 2002
- Composition and process140US 4,306,075 AThe Upjohn Company · 1981
- Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension118US 5,296,504 AKabi Pharmacia AB · 1994