A61L 27/54
Biologically active materials
Official title: Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)}
A61L27/54 (Biologically active materials) appears on 5,266 US grants and 8,860 published applications in this corpus.
Search patents in A61L- Granted patents
- 5,266
- Published applications
- 8,860
- Assignees
- 2,949
- Inventors
- 13,087
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 2 | 0 |
| 1977 | 2 | 0 |
| 1978 | 2 | 0 |
| 1979 | 0 | 0 |
| 1980 | 6 | 0 |
| 1981 | 4 | 0 |
| 1982 | 3 | 0 |
| 1983 | 2 | 0 |
| 1984 | 3 | 0 |
| 1985 | 3 | 0 |
| 1986 | 10 | 0 |
| 1987 | 6 | 0 |
| 1988 | 7 | 0 |
| 1989 | 14 | 0 |
| 1990 | 21 | 0 |
| 1991 | 18 | 0 |
| 1992 | 14 | 0 |
| 1993 | 23 | 0 |
| 1994 | 38 | 0 |
| 1995 | 26 | 0 |
| 1996 | 29 | 0 |
| 1997 | 44 | 0 |
| 1998 | 65 | 0 |
| 1999 | 51 | 0 |
| 2000 | 47 | 0 |
| 2001 | 50 | 29 |
| 2002 | 53 | 97 |
| 2003 | 62 | 132 |
| 2004 | 53 | 162 |
| 2005 | 54 | 247 |
| 2006 | 42 | 212 |
| 2007 | 57 | 252 |
| 2008 | 43 | 273 |
| 2009 | 58 | 246 |
| 2010 | 104 | 322 |
| 2011 | 145 | 326 |
| 2012 | 171 | 305 |
| 2013 | 210 | 393 |
| 2014 | 305 | 441 |
| 2015 | 322 | 517 |
| 2016 | 301 | 553 |
| 2017 | 341 | 486 |
| 2018 | 325 | 468 |
| 2019 | 317 | 561 |
| 2020 | 348 | 479 |
| 2021 | 313 | 495 |
| 2022 | 237 | 454 |
| 2023 | 247 | 382 |
| 2024 | 251 | 401 |
| 2025 | 272 | 371 |
| 2026 | 145 | 256 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Polymeric patch scaffolds for articular cartilage regeneration6 Oct 2026US 12,752,041 B2University of Southern California
- Nasal implants and systems and method of use29 Sep 2026US 12,746,114 B2Stryker Corporation
- Hydrogel systems for skeletal interfacial tissue regeneration applied to epiphyseal growth plate repair29 Sep 2026US 12,746,258 B2University of Pittsburgh—Of the Commonwealth System of Higher Education
- Hyaluronic acid derivative and use thereof29 Sep 2026US 12,746,306 B2Amtixbio Co., Ltd.
- Electron beam irradiated osteoinductive bone implant29 Sep 2026US 12,746,308 B2Warsaw Orthopedic, Inc.
- Bio-orthogonal hydrogels for sustained replease drug delivery8 Oct 2026US 2026/0306717 A1Ocular Therapeutix, Inc.
- Metal alloy having rhenium effect8 Oct 2026US 2026/0308726 A1MiRus LLC
- Metal alloy having rhenium effect8 Oct 2026US 2026/0308727 A1MiRus LLC
- Metal alloy having rhenium effect8 Oct 2026US 2026/0308728 A1MiRus LLC
- Metal alloy having rhenium effect8 Oct 2026US 2026/0308729 A1MiRus LLC
Most cited
By later US patents
- Drug releasing anastomosis devices and methods for treating anastomotic sites1,779US 7,108,701 B2Ethicon, Inc. · 2006
- Surgical implant and method for controlled release of chemotherapeutic agents1,679US 5,290,271 A1994
- Drug releasing biodegradable fiber implant1,662US 6,596,296 B1Board of Regents, The University of Texas System · 2003
- Microporous vascular graft1,647US 5,024,671 ABaxter International Inc. · 1991
- Particle immobilized coatings and uses thereof1,386US 8,679,454 B2SurModics, Inc. · 2014