Surgical implant and method for controlled release of chemotherapeutic agents

A surgical implant comprising a porous matrix, said matrix further containing time-release microshapes encapsulating at least one chemotherapeutic agent incorporated into said porous matrix, wherein said time-release microshapes will begin to release said at least one chemotherapeutic agent at a localized treatment site upon surgical implantation of said implant, said implant further containing means for improving the cellular uptake of said at least one chemotherapeutic agent at the localized treatment site upon surgical implantation of said implant, said means comprising at least one carrier agent incorporated into the matrix of said implant, said implant selected from the group consisting of a vascular graft, heart valve leaflet, ligament prosthesis, tendon prosthesis and urethral prosthesis.