A61K 51/0459
Having six-membered rings with two nitrogen atoms as the only ring hetero
Official title: {having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine}
A61K51/0459 (Having six-membered rings with two nitrogen atoms as the only ring hetero) appears on 302 US grants and 509 published applications in this corpus.
Search patents in A61K- Granted patents
- 302
- Published applications
- 509
- Assignees
- 226
- Inventors
- 1,051
- Latest grant
- 18 Aug 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 0 | 0 |
| 1987 | 0 | 0 |
| 1988 | 0 | 0 |
| 1989 | 0 | 0 |
| 1990 | 1 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 4 | 0 |
| 1995 | 1 | 0 |
| 1996 | 1 | 0 |
| 1997 | 4 | 0 |
| 1998 | 1 | 0 |
| 1999 | 2 | 0 |
| 2000 | 6 | 0 |
| 2001 | 4 | 2 |
| 2002 | 4 | 6 |
| 2003 | 7 | 10 |
| 2004 | 4 | 16 |
| 2005 | 6 | 7 |
| 2006 | 3 | 9 |
| 2007 | 4 | 13 |
| 2008 | 11 | 11 |
| 2009 | 6 | 15 |
| 2010 | 5 | 22 |
| 2011 | 5 | 16 |
| 2012 | 10 | 16 |
| 2013 | 12 | 19 |
| 2014 | 11 | 35 |
| 2015 | 14 | 23 |
| 2016 | 14 | 29 |
| 2017 | 28 | 30 |
| 2018 | 19 | 26 |
| 2019 | 22 | 24 |
| 2020 | 20 | 30 |
| 2021 | 15 | 24 |
| 2022 | 9 | 30 |
| 2023 | 14 | 17 |
| 2024 | 11 | 27 |
| 2025 | 5 | 24 |
| 2026 | 17 | 28 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Radiolabelled compound18 Aug 2026US 12,709,601 B2Oxford University Innovation Limited
- Small molecules for dual function positron emission tomography (PET) and cell suicide switches4 Aug 2026US 12,697,403 B2The Trustees of the University of Pennsylvania
- Brand-new skeleton 99MTC-FAPI diagnostic probe and use thereof in preparation of drug or reagent for diagnosing tumors14 Jul 2026US 12,678,519 B2Nanjing Nuoyuan Medical Devices Co., Ltd
- Isoindolinone compounds and imaging agents for imaging Huntingtin protein23 Jun 2026US 12,661,415 B2CHDI Foundation, Inc.
- Selective ligands for tau aggregates26 May 2026US 12,636,385 B2Sentonix, Inc.
- Isoindolinone compounds and imaging agents for imaging huntingtin protein24 Sep 2026US 2026/0284234 A1CHDI Foundation, Inc.
- Radiolabeled fapi complex, and preparation method therefor and use thereof24 Sep 2026US 2026/0284237 A1Beijing Normal University
- Liquid composition of compound i, preparation method therefor, and application thereof3 Sep 2026US 2026/0256955 A1Beijing Sinotau International Pharmaceutical Technology Co., Ltd.
- Stabilized radiopharmaceutical compositions3 Sep 2026US 2026/0256956 A1Jubilant Draximage Inc.
- Radiotracer for positron emission tomography (pet) imaging of alpha1a adrenoceptors in human brain27 Aug 2026US 2026/0248971 A1The United States Government as represented by the Department of Veterans Affairs
Most cited
By later US patents
- Glycine receptor antagonists and the use thereof159US 5,514,680 AState of Oregon, acting by and through the Oregon State Board of Higher Education, acting for and on behalf of the Oregon Health Sciences University · 1996
- Vitamin-targeted imaging agents155US 7,128,893 B2Endocyte, Inc. · 2006
- Composition and method for tumor imaging123US 5,688,488 APurdue Research Foundation · 1997
- Radiolabeled farnesyl-protein transferase inhibitors111US 6,060,038 AMerck & Co., Inc. · 2000
- Metal complexes derivatized with folate for use in diagnostic and therapeutic applications84US 6,093,382 ABracco Research USA · 2000