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US 12,661,415 B2Granted
Isoindolinone compounds and imaging agents for imaging Huntingtin protein
AssigneeCHDI Foundation, Inc.
InventorsLongbin Liu, Celia Dominguez, Jonathan Bard, Christopher John Brown, Xuemei Chen, Daniel Clark-Frew, Matthew Robert Mills, Peter David Johnson, Elise Gadouleau
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Abstract
Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
Claims10
A compound that is:
- or an isotopically enriched analog, pharmaceutically acceptable salt, tautomer, stereoisomer, or a mixture of stereoisomers thereof, optionally wherein the compound is labeled with a radioactive isotope.
Dependencies are inferred from the claim text.