A61K 49/0032
Methine dyes
Official title: {Methine dyes, e.g. cyanine dyes}
A61K49/0032 (Methine dyes) appears on 906 US grants and 1,625 published applications in this corpus.
Search patents in A61K- Granted patents
- 906
- Published applications
- 1,625
- Assignees
- 638
- Inventors
- 3,057
- Latest grant
- 8 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1988 | 1 | 0 |
| 1989 | 1 | 0 |
| 1990 | 0 | 0 |
| 1991 | 0 | 0 |
| 1992 | 0 | 0 |
| 1993 | 1 | 0 |
| 1994 | 1 | 0 |
| 1995 | 2 | 0 |
| 1996 | 1 | 0 |
| 1997 | 5 | 0 |
| 1998 | 3 | 0 |
| 1999 | 6 | 0 |
| 2000 | 6 | 0 |
| 2001 | 14 | 3 |
| 2002 | 10 | 9 |
| 2003 | 10 | 24 |
| 2004 | 7 | 23 |
| 2005 | 5 | 21 |
| 2006 | 8 | 28 |
| 2007 | 7 | 33 |
| 2008 | 13 | 37 |
| 2009 | 14 | 50 |
| 2010 | 11 | 49 |
| 2011 | 16 | 72 |
| 2012 | 25 | 47 |
| 2013 | 29 | 75 |
| 2014 | 45 | 68 |
| 2015 | 38 | 74 |
| 2016 | 45 | 85 |
| 2017 | 78 | 94 |
| 2018 | 46 | 90 |
| 2019 | 76 | 88 |
| 2020 | 79 | 120 |
| 2021 | 67 | 95 |
| 2022 | 48 | 87 |
| 2023 | 59 | 97 |
| 2024 | 52 | 103 |
| 2025 | 47 | 88 |
| 2026 | 30 | 65 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
Recent patents
- Heptamethine cyanine near-infrared fluorescent dye, preparation method therefor and use thereof8 Sep 2026US 12,728,173 B2Nanjing Nuoyuan Medical Devices Co., Ltd
- Compound, preparation method therefor, composition, kit and use thereof25 Aug 2026US 12,715,844 B2Signdo Biotechnology (Suzhou) Co., Ltd
- Functionalized silica nanorings, methods of making same, and uses thereof11 Aug 2026US 12,703,637 B2Cornell University
- Thrombus imaging aptamers and methods of using same4 Aug 2026US 12,697,401 B2Duke University
- Detection of colonic neoplasia in vivo using near-infrared peptide targeted against overexpressed cMet4 Aug 2026US 12,697,402 B2The Regents of the University of Michigan
- Method for Medical Imaging1 Oct 2026US 2026/0294251 A1Integro Theranositcs, LLC
- Modified cyanine dyes and conjugates thereof17 Sep 2026US 2026/0274824 A1Bracco Imaging S.P.A.
- N-oxide based zwitterionic near infrared fluorophore imaging agents and methods of use therefor10 Sep 2026US 2026/0263642 A1Curadel Surgical Innovations, Inc.
- Mutant fab fragment for obtaining site-specific mono-or bifunctionalised conjugates10 Sep 2026US 2026/0265367 A1
- Peptide multimer products and methods27 Aug 2026US 2026/0248969 A1The Regents of the University of Michigan
Most cited
By later US patents
- Devices and methods for monitoring drug therapy compliance214US 6,663,846 B12003
- Intramolecularly-quenched near infrared fluorescent probes148US 6,083,486 AThe General Hospital Corporation · 2000
- Tumor-targeted optical contrast agents142US 7,198,778 B2Mallinckrodt Inc. · 2007
- Acid-labile and enzymatically divisible dye compounds for diagnosis with near infrared light and for therapy139US 6,534,041 B1Institute for Diagnostic Research GmbH of the Free University of Berlin · 2003
- Nucleotide compositions comprising photocleavable markers and methods of preparation thereof131US 7,057,031 B2AmberGen, Inc. · 2006