A61K 49/00
Preparations for testing in vivo
A61K49/00 (Preparations for testing in vivo) appears on 9,485 US grants and 13,965 published applications in this corpus.
Search patents in A61K- Granted patents
- 9,485
- Published applications
- 13,965
- Assignees
- 4,549
- Inventors
- 24,776
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 8 | 0 |
| 1977 | 15 | 0 |
| 1978 | 14 | 0 |
| 1979 | 4 | 0 |
| 1980 | 7 | 0 |
| 1981 | 8 | 0 |
| 1982 | 11 | 0 |
| 1983 | 8 | 0 |
| 1984 | 9 | 0 |
| 1985 | 11 | 0 |
| 1986 | 13 | 0 |
| 1987 | 31 | 0 |
| 1988 | 27 | 0 |
| 1989 | 49 | 0 |
| 1990 | 36 | 0 |
| 1991 | 59 | 0 |
| 1992 | 73 | 0 |
| 1993 | 93 | 0 |
| 1994 | 135 | 0 |
| 1995 | 155 | 0 |
| 1996 | 171 | 0 |
| 1997 | 213 | 0 |
| 1998 | 229 | 0 |
| 1999 | 185 | 0 |
| 2000 | 188 | 0 |
| 2001 | 191 | 76 |
| 2002 | 171 | 288 |
| 2003 | 186 | 396 |
| 2004 | 115 | 389 |
| 2005 | 123 | 481 |
| 2006 | 152 | 419 |
| 2007 | 121 | 430 |
| 2008 | 142 | 427 |
| 2009 | 140 | 476 |
| 2010 | 196 | 556 |
| 2011 | 199 | 601 |
| 2012 | 266 | 496 |
| 2013 | 339 | 632 |
| 2014 | 424 | 759 |
| 2015 | 444 | 769 |
| 2016 | 442 | 796 |
| 2017 | 571 | 702 |
| 2018 | 439 | 707 |
| 2019 | 537 | 697 |
| 2020 | 508 | 738 |
| 2021 | 447 | 666 |
| 2022 | 381 | 576 |
| 2023 | 350 | 529 |
| 2024 | 326 | 558 |
| 2025 | 314 | 453 |
| 2026 | 209 | 348 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Subgroups
Granted patents
- A61K 49/001Preparation for luminescence or biological staining3,543
- A61K 49/06Nuclear magnetic resonance [nmr] contrast preparations2,797
- A61K 49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions1,718
- A61K 49/04X-ray contrast preparations1,244
- A61K 49/22Echographic preparations993
- A61K 49/0002General or multifunctional contrast agents867
Recent patents
- Method and apparatus for measuring intravascular blood flow using a backscattering contrast6 Oct 2026US 12,751,639 B2The General Hospital Corporation
- Tumor-targeting Salmonella gallinarum strain and use thereof6 Oct 2026US 12,751,978 B2Industry Foundation of Chonnam National University
- Single-polymer particles, active molecular complex, method for producing single-polymer particles, method for measuring tumor size, method for measuring fine structure within tumor, method for imaging biological tissue, drug delivery system, and contrast agent kit6 Oct 2026US 12,752,022 B2National Institutes for Quantum Science and Technology
- Peptide libraries with non-canonical amino acids6 Oct 2026US 12,753,205 B2Regeneron Pharmaceuticals, Inc.
- Antibody conjugates and uses thereof6 Oct 2026US 12,753,242 B2GlycoNex Inc.
- Genetically Modified Non-Human Animals and Methods of Use Thereof8 Oct 2026US 2026/0305588 A1Institute for Research in Biomedicine (IRB)
- Ultrasound coupling agent8 Oct 2026US 2026/0306057 A1Sonoclear AS
- Biosensor performance indicator for intraoral appliances8 Oct 2026US 2026/0306232 A1Align Technology, Inc.
- Method for synthesizing zeolite nanoparticles in a saline phosphate buffer and associated nanoparticles, suspensions, pharmaceutical composition and uses8 Oct 2026US 2026/0306532 A1Centre National De La Recherche Scientifique
- Long-Lived Gadolinium Based Tumor Targeted Imaging and Therapy Agents8 Oct 2026US 2026/0306634 A1Wisconsin Alumni Research Foundation
Most cited
By later US patents
- Medical scanning and treatment system and method1,502US 5,464,013 A1995
- Particle immobilized coatings and uses thereof1,386US 8,679,454 B2SurModics, Inc. · 2014
- Imageable biopsy site marker1,164US 6,996,433 B2SenoRx, Inc. · 2006
- Surface modified drug nanoparticles993US 5,145,684 ASterling Drug Inc. · 1992
- Microporation of human skin for monitoring the concentration of an analyte944US 5,885,211 AAltea Technologies, Inc. · 1999