A61K 48/0091
Purification or manufacturing processes for gene therapy compositions
Official title: {Purification or manufacturing processes for gene therapy compositions}
A61K48/0091 (Purification or manufacturing processes for gene therapy compositions) appears on 249 US grants and 565 published applications in this corpus.
Search patents in A61K- Granted patents
- 249
- Published applications
- 565
- Assignees
- 272
- Inventors
- 988
- Latest grant
- 6 Oct 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 2 | 0 |
| 2002 | 2 | 8 |
| 2003 | 3 | 14 |
| 2004 | 6 | 12 |
| 2005 | 2 | 11 |
| 2006 | 7 | 15 |
| 2007 | 5 | 15 |
| 2008 | 4 | 14 |
| 2009 | 4 | 15 |
| 2010 | 1 | 11 |
| 2011 | 3 | 9 |
| 2012 | 5 | 14 |
| 2013 | 7 | 10 |
| 2014 | 11 | 12 |
| 2015 | 10 | 11 |
| 2016 | 6 | 21 |
| 2017 | 9 | 17 |
| 2018 | 7 | 24 |
| 2019 | 17 | 57 |
| 2020 | 15 | 31 |
| 2021 | 25 | 36 |
| 2022 | 19 | 52 |
| 2023 | 18 | 37 |
| 2024 | 31 | 31 |
| 2025 | 18 | 45 |
| 2026 | 11 | 43 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Methods of preparation of pan TLR antagonistic liposomal-LNP formulations and uses thereof6 Oct 2026US 12,751,920 B2Celestial Therapeutics, Inc.
- Processes of preparing mRNA-loaded lipid nanoparticles15 Sep 2026US 12,734,253 B2Translate Bio, Inc.
- Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related thereto1 Sep 2026US 12,721,909 B2The University of British Columbia
- Rapid design, build, test, and learn technologies for identifying and using non-viral carriers18 Aug 2026US 12,709,747 B2Battelle Memorial Institute
- TES-based cationic lipids16 Jun 2026US 12,655,095 B2Translate Bio, Inc.
- Engineered compact crispr-cas12f system8 Oct 2026US 2026/0308554 A1
- An intelligent charge switchable polymer-lipid hybrid system for in vivo delivery of molecules including rnas1 Oct 2026US 2026/0294830 A1Qurcan Therapeutics Inc.
- Nannochloropsis-producing viruses and methods and compositions for making the same1 Oct 2026US 2026/0297502 A1Insmed Incorporated
- 5’-c alkyl substituted rna caps and methods of use17 Sep 2026US 2026/0272969 A1Nutcracker Therapeutics, Inc.
- Compositions and methods to improve rna properties using base, phosphodiester linkage, sugar backbone, and cap modifications10 Sep 2026US 2026/0263638 A1Massachusetts Institute of Technology
Most cited
By later US patents
- Compositions and methods for helper-free production of recombinant adeno-associated viruses159US 6,953,690 B1The Trustees of the University of Pennsylvania · 2005
- Apparatus and method for electroporation of biological samples114US 7,141,425 B2MaxCyte, Inc. · 2006
- Methods for treating cancer using cytokine-expressing polynucleotides114US 7,268,120 B1Vical Incorporated · 2007
- Methods for generating high titer helper-free preparations of released recombinant AAV vectors75US 6,989,264 B2Targeted Genetics Corporation · 2006
- Methods for generating high titer helper-free preparations of released recombinant AAV vectors75US 6,995,006 B2Targeted Genetics Corporation · 2006