A61K 41/0042
Photocleavage of drugs in vivo
Official title: {Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion}
A61K41/0042 (Photocleavage of drugs in vivo) appears on 238 US grants and 366 published applications in this corpus.
Search patents in A61K- Granted patents
- 238
- Published applications
- 366
- Assignees
- 227
- Inventors
- 803
- Latest grant
- 2 Jun 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1980 | 1 | 0 |
| 1981 | 0 | 0 |
| 1982 | 0 | 0 |
| 1983 | 0 | 0 |
| 1984 | 0 | 0 |
| 1985 | 0 | 0 |
| 1986 | 1 | 0 |
| 1987 | 1 | 0 |
| 1988 | 0 | 0 |
| 1989 | 1 | 0 |
| 1990 | 1 | 0 |
| 1991 | 1 | 0 |
| 1992 | 3 | 0 |
| 1993 | 0 | 0 |
| 1994 | 0 | 0 |
| 1995 | 2 | 0 |
| 1996 | 3 | 0 |
| 1997 | 3 | 0 |
| 1998 | 4 | 0 |
| 1999 | 6 | 0 |
| 2000 | 4 | 0 |
| 2001 | 4 | 1 |
| 2002 | 7 | 13 |
| 2003 | 11 | 10 |
| 2004 | 6 | 11 |
| 2005 | 4 | 9 |
| 2006 | 3 | 10 |
| 2007 | 5 | 11 |
| 2008 | 6 | 9 |
| 2009 | 5 | 17 |
| 2010 | 5 | 8 |
| 2011 | 5 | 12 |
| 2012 | 10 | 10 |
| 2013 | 5 | 13 |
| 2014 | 11 | 23 |
| 2015 | 10 | 19 |
| 2016 | 16 | 19 |
| 2017 | 14 | 15 |
| 2018 | 11 | 15 |
| 2019 | 10 | 21 |
| 2020 | 12 | 26 |
| 2021 | 9 | 16 |
| 2022 | 8 | 21 |
| 2023 | 10 | 16 |
| 2024 | 9 | 23 |
| 2025 | 7 | 12 |
| 2026 | 4 | 6 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Delivery carrier into cell2 Jun 2026US 12,642,769 B2Kabusikikaisya ITO
- Platinum(IV) complexes, methods of manufacture, compositions containing, and methods of use thereof5 May 2026US 12,617,812 B2City University of Hong Kong
- Photolytic compounds and triplet-triplet annihilation mediated photolysis14 Apr 2026US 12,599,666 B2University of Massachusetts
- Efficient synthesis of lipid-fluorescein conjugates for CAR-T cell therapy31 Mar 2026US 12,589,155 B2Purdue Research Foundation
- Macromolecular prodrugs for light-emitting diodes and uses thereof30 Sep 2025US 12,427,196 B2Children's Medical Center Corporation
- Cytotoxic agent24 Sep 2026US 2026/0284193 A1
- New psoralen compound30 Jul 2026US 2026/0216336 A1Nagasaki University
- Radioluminescent nanoparticles for radiation-triggered controlled release drugs2 Jul 2026US 2026/0183398 A1Purdue Research Foundation
- Macromolecular prodrugs for light-emitting diodes and uses thereof4 Jun 2026US 2026/0151485 A1Children's Medical Center Corporation
- Fiber optic probe for therapeutic use7 May 2026US 2026/0124460 A1Rakuten Medical, Inc.
Most cited
By later US patents
- Antibody conjugates for the delivery of compounds to target sites546US 4,671,958 ACytogen Corporation · 1987
- Optically-active nanoparticles for use in therapeutic and diagnostic methods434US 6,530,944 B2Rice University · 2003
- Method of expanded porphyrin-oligonucleotide conjugate synthesis325US 5,565,552 ABoard of Regents, Univ. of Texas Sys. · 1996
- Metal nanoshells299US 6,344,272 B12002
- Antibody-therapeutic agent conjugates288US 4,867,973 ACytogen Corporation · 1989