Cytotoxic agent
OwnerDonny DE BRUIN, Dirk BOUWMEESTER +1inventors
InventorsDonny DE BRUIN, Dirk BOUWMEESTER, Doris Marianne HEINRICH
Life of this patent
Estimating the term…
Abstract
Provided is a cytotoxic agent which is activatable by exposure to light. The agent comprises a metal cluster and a molecule comprising a photocleavable group. The molecule forms a structure which at least partially encloses the metal cluster so as to prevent the metal cluster from interacting with a surrounding environment and wherein, upon exposure to light, cleavage of the photocleavable group changes the structure of the molecule such that the metal cluster is able to interact with the surrounding environment.
Claims20
An agent comprising a metal cluster and a molecule comprising a photocleavable group, wherein the molecule forms a structure which at least partially encloses the metal cluster so as to prevent the metal cluster from interacting with a surrounding environment and wherein, upon exposure to light, cleavage of the photocleavable group changes the structure of the molecule such that the metal cluster is able to interact with the surrounding environment.
The agent of any preceding claim, wherein the photocleavable group is cleavable by light having a wavelength of from 315 nm to 2000 nm.
The agent of any preceding claim, wherein the metal cluster comprises or consists of silver.
The agent of any preceding claim, wherein the metal cluster comprises no more than 20 atoms.
Dependencies are inferred from the claim text.