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US 2026/0216336 A1Published application
New psoralen compound
AssigneeNagasaki University
InventorsAsako YAMAYOSHI, Yu MIKAME, Juki NAKAO
Life of this patent
Estimating the term…
Abstract
The present invention provides a compound represented by the following formula (I): [each symbol in formula (I) is as described in the accompanying description], or a salt thereof.
Claims17
A compound represented by the following formula (I) or a salt thereof:
- wherein
- R1 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R7 [where R7 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms], or is represented by the following formula (II-1), (II-2), or (II-3):
- [in the formulae (II-1), (II-2), and (II-3), R8 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —N(R9)2 or —O—R9 [where R9 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms]],
- R2 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R10 [where R10 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms],
- R3 and R4 are each independently a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, —O—R11 [where R11 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms], or a phenyl group or naphthyl group in which each hydrogen atom may be substituted with an aliphatic group having 1 to 3 carbon atoms, or alternatively,
- R3 and R4 together form a benzene ring or naphthyl ring in which each hydrogen atom may be substituted with an aliphatic group having 1 to 3 carbon atoms,
- R5 is represented by the following Formula (III-1) or (III-2):
- [in the formulae (III-1) and (III-2),
- m is an integer of 0 to 4,
- n is an integer of 1 to 5, and
- R13 and R14 are each independently a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or a polar group], and
- R6 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R12 [where R12 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms].
9 more elements
(canceled)
A nucleic acid having a structure represented by the following formula (V-1), (V-2), (V-3), or (V-4):
- [in the formulae (V-1), (V-2), (V-3), and (V-4),
- R1 is independently a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R7 [where R7 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms], or is represented by the following formula (II-1), (II-2), or (II-3):
- [in the formulae (II-1), (II-2), and (II-3), R8 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —N(R9)2 or —O—R9 [where R9 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms]],
- R2 is a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R10 [where R10 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms],
- R3 and R4 are each independently a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, —O—Ru [where R11 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms], or a phenyl group or naphthyl group in which each hydrogen atom may be substituted with an aliphatic group having 1 to 3 carbon atoms, or alternatively,
- R3 and R4 together form a benzene ring or naphthyl ring in which each hydrogen atom may be substituted with an aliphatic group having 1 to 3 carbon atoms,
- R5 and R6 are each independently a hydrogen atom, an aliphatic group having 1 to 3 carbon atoms, or —O—R12 [where R12 is a hydrogen atom or an aliphatic group having 1 to 3 carbon atoms],
- m is an integer of 0 to 4, and
- n is an integer of 1 to 5].
6 more elements
Dependencies are inferred from the claim text.