A61K 38/1761
Apoptosis related proteins
Official title: {Apoptosis related proteins, e.g. Apoptotic protease-activating factor-1 (APAF-1), Bax, Bax-inhibitory protein(s)(BI; bax-I), Myeloid cell leukemia associated protein (MCL-1), Inhibitor of apoptosis [IAP] or Bcl-2}
A61K38/1761 (Apoptosis related proteins) appears on 142 US grants and 278 published applications in this corpus.
Search patents in A61K- Granted patents
- 142
- Published applications
- 278
- Assignees
- 143
- Inventors
- 438
- Latest grant
- 29 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1999 | 1 | 0 |
| 2000 | 0 | 0 |
| 2001 | 0 | 1 |
| 2002 | 0 | 3 |
| 2003 | 0 | 2 |
| 2004 | 1 | 4 |
| 2005 | 0 | 2 |
| 2006 | 0 | 4 |
| 2007 | 0 | 4 |
| 2008 | 1 | 5 |
| 2009 | 1 | 4 |
| 2010 | 3 | 11 |
| 2011 | 1 | 9 |
| 2012 | 1 | 5 |
| 2013 | 4 | 7 |
| 2014 | 3 | 9 |
| 2015 | 4 | 16 |
| 2016 | 10 | 28 |
| 2017 | 7 | 16 |
| 2018 | 11 | 13 |
| 2019 | 15 | 31 |
| 2020 | 13 | 29 |
| 2021 | 8 | 14 |
| 2022 | 16 | 16 |
| 2023 | 18 | 10 |
| 2024 | 4 | 18 |
| 2025 | 13 | 14 |
| 2026 | 7 | 3 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Fas-associated factor 1 (FAF1)-loaded exosomes and use thereof as anti-cancer agent29 Sep 2026US 12,746,271 B2Kainos Medicine, Inc.
- Selective MCL-1 binding peptides22 Sep 2026US 12,741,997 B2Massachusetts Institute of Technology
- Engineered peptide and peptide mimetic compositions and methods23 Jun 2026US 12,662,518 B2The Wistar Institute of Anatomy and Biology
- Anti-senescence compounds and uses thereof16 Jun 2026US 12,653,862 B2Cleara Biotech B.V.
- Dominant negative SARM1 molecules comprising a substitution at position 189, 190, 193, 194, 570 and/or 685 of SARM117 Mar 2026US 12,576,130 B2Washington University
- Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive noxa peptides6 Aug 2026US 2026/0226104 A1Dana-Farber Cancer Institute, Inc.
- Methods of treating cancers14 May 2026US 2026/0130910 A1
- Bag3 methods and uses for treatment of inflammation1 Jan 2026US 2026/0000789 A1Loyola University of Chicago
- Compositions and methods for antigen-specific tolerance25 Dec 2025US 2025/0387461 A1Myelin Repair Foundation, Inc.
- Compositions and methods for delivery of biomacromolecule agents11 Dec 2025US 2025/0375388 A1The Regents of the University of Michigan
Most cited
By later US patents
- Methods for treating arthritis by administering an apoptosis regulator43US 6,004,942 AThe Regents of the University of California · 1999
- High affinity PD-1 agents and methods of use40US 9,562,087 B2The Board of Trustees of the Leland Stanford Junior University · 2017
- Therapeutic peptidomimetic macrocycles38US 8,808,694 B2Aileron Therapeutics, Inc. · 2014
- High affinity PD-1 agents and methods of use35US 9,546,206 B2The Board of Trustees of the Leland Stanford Junior University · 2017
- IAP BIR domain binding compounds23US 7,579,320 B2Aegera Therapeutics, Inc. · 2009