A61K 31/475
Having an indole ring
Official title: having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine (vincamine A61K31/4375)
A61K31/475 (Having an indole ring) appears on 857 US grants and 1,363 published applications in this corpus.
Search patents in A61K- Granted patents
- 857
- Published applications
- 1,363
- Assignees
- 764
- Inventors
- 2,753
- Latest grant
- 22 Sep 2026
Filings by year
| Year | Granted patents | Published applications |
|---|---|---|
| 1976 | 4 | 0 |
| 1977 | 3 | 0 |
| 1978 | 3 | 0 |
| 1979 | 1 | 0 |
| 1980 | 6 | 0 |
| 1981 | 4 | 0 |
| 1982 | 6 | 0 |
| 1983 | 0 | 0 |
| 1984 | 2 | 0 |
| 1985 | 3 | 0 |
| 1986 | 4 | 0 |
| 1987 | 1 | 0 |
| 1988 | 3 | 0 |
| 1989 | 3 | 0 |
| 1990 | 11 | 0 |
| 1991 | 3 | 0 |
| 1992 | 3 | 0 |
| 1993 | 10 | 0 |
| 1994 | 7 | 0 |
| 1995 | 10 | 0 |
| 1996 | 13 | 0 |
| 1997 | 27 | 0 |
| 1998 | 23 | 0 |
| 1999 | 17 | 0 |
| 2000 | 17 | 0 |
| 2001 | 15 | 3 |
| 2002 | 13 | 22 |
| 2003 | 14 | 37 |
| 2004 | 10 | 40 |
| 2005 | 12 | 25 |
| 2006 | 8 | 17 |
| 2007 | 8 | 17 |
| 2008 | 4 | 38 |
| 2009 | 2 | 30 |
| 2010 | 7 | 39 |
| 2011 | 18 | 26 |
| 2012 | 21 | 52 |
| 2013 | 30 | 62 |
| 2014 | 38 | 71 |
| 2015 | 40 | 73 |
| 2016 | 35 | 100 |
| 2017 | 49 | 87 |
| 2018 | 46 | 70 |
| 2019 | 55 | 71 |
| 2020 | 44 | 61 |
| 2021 | 43 | 93 |
| 2022 | 34 | 78 |
| 2023 | 43 | 94 |
| 2024 | 28 | 61 |
| 2025 | 34 | 56 |
| 2026 | 22 | 40 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
- Polypeptide that specifically binding to CD123 protein, polypeptide complex, co-delivery system and preparation method and use thereof22 Sep 2026US 12,742,016 B2Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
- Methods of treating breast cancer15 Sep 2026US 12,738,355 B2City of Hope
- Dosing for treatment with anti-CD20/anti-CD3 bispecific antibody8 Sep 2026US 12,729,243 B2Hoffmann-La Roche Inc.
- Method of treating triple-negative breast cancer25 Aug 2026US 12,714,691 B2Dana-Farber Cancer Institute, Inc.
- Apparatus, methods, and systems for providing pharmaceutical compositions in the form of droplets for aerosol administration and inhalation delivery25 Aug 2026US 12,714,705 B2
- Inverse agonists of rar related orphan receptors (rors)8 Oct 2026US 2026/0306484 A111949098 CANADA INC. (NUREDCO) c/o Jean I. TCHERVENKOV
- Methionine adenosyltransferase 2a (mat2a) inhibitor combinations and uses thereof24 Sep 2026US 2026/0284051 A1Insilico Medicine IP Limited
- Methods for Treating Metastatic Pancreatic Cancer Using Combination Therapies Comprising Liposomal Irinotecan and Oxaliplatin24 Sep 2026US 2026/0284054 A1Ipsen Biopharm Ltd.
- Stem cell-derived ecto-liposome fusion nanoparticles and use thereof10 Sep 2026US 2026/0263362 A1Ectosome Inc.
- Dual-composite delivery system10 Sep 2026US 2026/0263601 A1University of Washington
Most cited
By later US patents
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- Combination therapies for B-cell lymphomas comprising administration of anti-CD20 antibody199US 6,455,043 B1IDEC Pharmaceuticals Corporation · 2002
- Compositions and methods for treating surgical adhesions160US 6,689,803 B2Angiotech Pharmaceuticals, Inc. · 2004
- Drug loaded polymeric nanoparticles and methods of making and using same119US 8,420,123 B2Bind Biosciences, Inc. · 2013
- Drug loaded polymeric nanoparticles and methods of making and using same111US 8,617,608 B2BIND Therapeutics, Inc. · 2013