C12P 37/04
Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system: by acylation
Official title: by acylation of the substituent in the 6 position
C12P37/04 (Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system: by acylation) appears on 27 US grants and 13 published applications in this corpus.
Search patents in C12P- Granted patents
- 27
- Published applications
- 13
- Assignees
- 17
- Inventors
- 77
- Latest grant
- 18 Nov 2025
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| 2017 | 1 | 1 |
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| 2025 | 1 | 0 |
| 2026 | 0 | 2 |
By publication year. Applications have been published since 2001. 2026 runs to 8 Oct.
Recent patents
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- Enzyme-immobilized porous membrane and preparation method of antibiotics using the same14 Jun 2022US 11,359,224 B2Gwangju Institute of Science and Technology
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- Stable biocatalysts of penicillin acylase as gel aggregates and the process of manufacture thereof17 Jun 2014US 8,753,856 B2Fermenta Biotech Limited
- Mutant penicillin G acylases24 Sep 2013US 8,541,199 B2DSM Sinochem Pharmaceuticals Netherlands B.V.
- Biosynthesis of beta-lactam antibiotics24 Sep 2026US 2026/0286334 A1
- Mutant penicillin acylase and uses thereof30 Apr 2026US 2026/0117216 A1Xingzhi College Zhejiang Normal University
- Enzyme-immobilized porous membrane and preparation method of antibiotics using the same27 Feb 2020US 2020/0063175 A1Gwangju Institute of Science and Technology
- Enzyme-immobilized porous membrane and preparation method of antibiotics using the same13 Apr 2017US 2017/0101660 A1Gwangju Institute of Science and Technology
- Micronized amoxicillin14 Jul 2016US 2016/0199301 A1DSM Sinochem Pharmaceuticals Netherlands B.V.
Most cited
By later US patents
- Bioprocess for preparing 7-ACA and 7-ADAC10US 5,559,005 AMerck & Co., Inc. · 1996
- Enzymatic synthesis of .beta.-lactam antibacterials9US 4,340,672 AShionogi & Co., Ltd. · 1982
- Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)8US 5,318,896 AMerck & Co., Inc. · 1994
- Recombinant bioprocess for the preparation of 7-amino cephalosporanic acid (7-ACA)5US 5,629,171 AGist-Brocades N. V. · 1997
- Process of producing B-lactam antibiotics applying microorganisms with increased ligase activity4US 5,942,411 AGist-Brocades N. V. · 1999