Micronized amoxicillin
AssigneeDSM Sinochem Pharmaceuticals Netherlands B.V.
InventorsRajinder KAPOOR, Naresh SHARMA, Neeraj TEWARI
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Abstract
The present invention relates to amoxicillin trihydrate compositions having a surface area of from 1.0 to 2.5 m2·g−1 that are free of organic contaminants such as dichloromethane, isopropanol, pivalic acid and triethyl amine and that have a purity of from 97.0% to 99.99%. Furthermore, the present invention relates to a method for the preparation of said amoxicillin trihydrate compositions and to the use of said compositions for the treatment of a bacterial infection.
Claims11
Composition comprising from 97.0% to 99.99% (w/w) of amoxicillin trihydrate, having a surface area of from 1.0 to 2.5 m2·g−1, characterized in that it further comprises less than 500 ppm of a compound chosen from the list consisting of dichloromethane, isopropanol, pivalic acid and triethyl amine.
Dependencies are inferred from the claim text.